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Article: Aging decreases L-type calcium channel currents and pacemaker firing fidelity in substantia nigra dopamine neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Branch SY; Sharma R; Beckstead MJ
J. Neurosci., 2014

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Substantia nigra pars compacta dopaminergic cell cell capacitance (pF) 29.78 ± 0.67 (41) 29.78 (pF) Data Table
Substantia nigra pars compacta dopaminergic cell cell capacitance (pF) 30.98 ± 0.88 (45) 30.98 (pF) Data Table
Substantia nigra pars compacta dopaminergic cell input resistance 181.5 ± 10.4 (45) 181.5 (MΩ) Data Table
Substantia nigra pars compacta dopaminergic cell input resistance 191.9 ± 11.6 (41) 191.9 (MΩ) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
Strain C57BL
ElectrodeType Patch-clamp
PrepType in vitro
JxnPotential Corrected
AnimalAge 60.0 - 900.0
AnimalWeight 28.8 - 31.8
RecTemp 34.0
InternalSolution 5.0
ExternalSolution 5.0
internal_0_pH 7.375
internal_0_Mg 1.5
internal_0_Na 20.0
internal_0_K 115.0
internal_0_GTP 0.4
internal_0_ATP 2.0
internal_0_EGTA 0.025
internal_0_HEPES 10.0
internal_0_Cl 23.0
external_0_Mg 1.2
external_0_Na 152.4
external_0_K 2.5
external_0_Cl 135.7
external_0_Ca 2.4
external_0_glucose 11.0
external_0_kynur 1.25

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
50037 Aging decreases L-type calcium channel currents and pacemaker firing fidelity in substantia nigra dopamine neurons. Branch SY; Sharma R; Beckstead MJ J. Neurosci. 2014 False 2 Shreejoy Tripathy, Dawson Born, 1