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Article: Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Harb K; Magrinelli E; Nicolas CS; Lukianets N; Frangeul L; Pietri M; Sun T; Sandoz G; Grammont F; Jabaudon D; Studer M; Alfano C
Elife, 2016

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron adaptation ratio (at) 0.12 ± 0.02 (9) -- Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron adaptation ratio (at) 0.77 ± 0.1 (7) -- Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron adaptation ratio (at) 0.71 ± 0.08 (9) -- Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron ADP amplitude (mV) 6.32 ± 1.43 (7) 6.32 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron ADP amplitude (mV) 7.92 ± 1.07 (9) 7.92 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron ADP amplitude (mV) 4.71 ± 0.71 (9) 4.71 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron fast AHP amplitude (mV) 8.49 ± 1.27 (9) 8.49 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron fast AHP amplitude (mV) 10.23 ± 0.7 (7) 10.23 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron fast AHP amplitude (mV) 4.78 ± 1.23 (9) 4.78 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron fast AHP duration (ms) 1.37 ± 0.07 (9) 1.37 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron fast AHP duration (ms) 1.54 ± 0.1 (7) 1.54 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron fast AHP duration (ms) 1.38 ± 0.07 (9) 1.38 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron input resistance 86.0 ± 10.4 (7) 86.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron input resistance 56.7 ± 3.8 (9) 56.7 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron input resistance 46.4 ± 3.4 (9) 46.4 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron medium AHP amplitude (mV) 11.9 ± 1.3 (9) 11.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron medium AHP amplitude (mV) 13.7 ± 1.4 (7) 13.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron medium AHP amplitude (mV) 11.4 ± 1.1 (9) 11.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron medium AHP duration (ms) 34.7 ± 2.7 (9) 34.7 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron medium AHP duration (ms) 31.7 ± 5.2 (7) 31.7 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron medium AHP duration (ms) 25.3 ± 5.29 (9) 25.3 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron rheobase (pA) 0.3 ± 0.02 (9) -- Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron rheobase (pA) 0.39 ± 0.04 (9) -- Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron rheobase (pA) 0.26 ± 0.04 (7) -- Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron sag amplitude (mV) 1.2 ± 0.2 (9) 1.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron sag amplitude (mV) 3.1 ± 0.5 (9) 3.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron sag amplitude (mV) 4.8 ± 1.5 (7) 4.8 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron sag ratio 0.21 ± 0.02 (9) 0.21 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron sag ratio 0.12 ± 0.02 (9) 0.12 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron sag ratio 0.22 ± 0.03 (7) 0.22 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron spike amplitude (mV) 87.0 ± 3.9 (9) 87.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron spike amplitude (mV) 80.8 ± 5.8 (7) 80.8 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron spike amplitude (mV) 83.4 ± 4.8 (9) 83.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron spike half-width (ms) 0.77 ± 0.03 (9) 0.77 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron spike half-width (ms) 0.83 ± 0.04 (9) 0.83 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron spike half-width (ms) 0.85 ± 0.03 (7) 0.85 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron spike rise time (ms) 0.55 ± 0.02 (9) 0.55 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron spike rise time (ms) 0.59 ± 0.03 (9) 0.59 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron spike rise time (ms) 0.6 ± 0.04 (7) 0.6 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron spike threshold (mV) -40.6 ± 1.5 (9) -40.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron spike threshold (mV) -33.2 ± 4.8 (7) -33.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron spike threshold (mV) -42.1 ± 1.7 (9) -42.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing Satb2 expressing single-firing thick-tufted pyramidal neuron spike width (ms) 1.48 ± 0.07 (9) 1.48 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Satb2 expressing Ctip2 expressing double-firing thick-tufted pyramidal neuron spike width (ms) 1.69 ± 0.12 (9) 1.69 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer V Ctip2 expressing single-firing thick-tufted pyramidal neuron spike width (ms) 1.58 ± 0.07 (7) 1.58 (ms) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
JxnPotential Not corrected
AnimalAge 0.0 - 21.0
RecTemp 29.0
InternalSolution 5.0
ExternalSolution 5.0
Strain Thy1-YFP
internal_0_Mg 4.0
internal_0_Na 10.3
internal_0_K 120.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_HEPES 10.0
internal_0_Cl 20.0
external_0_Mg 1.0
external_0_Na 151.25
external_0_K 3.0
external_0_Cl 131.0
external_0_Ca 2.0
external_0_glucose 15.0
external_0_picro 0.05
external_0_DNQX 3.0
external_0_DAPV 2.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
50027 Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications. Harb K; Magrinelli E; Nicolas CS; Lukianets N; Frangeul L; Pietri M; Sun T; Sandoz G; Grammont F; Jabaudon D; Studer M; Alfano C Elife 2016 False 15 Shreejoy Tripathy, Dawson Born, 1