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Article: Differential effects of Na+-K+ ATPase blockade on cortical layer V neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Anderson TR; Huguenard JR; Prince DA
J. Physiol. (Lond.), 2010

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex basket cell Layer 5 somatosensory cortex Fast Spiking parvalbumin positive interneurons adaptation percent (1 – first/last ISI) 9.1 ± 5.9 (8) 9.1 (ratio) Data Table
Neocortex basket cell Layer 5 somatosensory cortex Fast Spiking parvalbumin positive interneurons cell capacitance (pF) 38.2 ± 5.3 (8) 38.2 (pF) Data Table
Neocortex basket cell Layer 5 somatosensory cortex Fast Spiking parvalbumin positive interneurons FI slope 120.8 ± 14.3 (8) 120.8 (Hz/nA) Data Table
Neocortex basket cell Layer 5 somatosensory cortex Fast Spiking parvalbumin positive interneurons firing frequency (Hz) 73.4 ± 35.3 (8) 73.4 (Hz) Data Table
Neocortex basket cell Layer 5 somatosensory cortex Fast Spiking parvalbumin positive interneurons input resistance 80.9 ± 8.5 (8) 80.9 (MΩ) Data Table
Neocortex basket cell Layer 5 somatosensory cortex Fast Spiking parvalbumin positive interneurons medium AHP amplitude (mV) 0.95 ± 0.1 (8) 0.95 (mV) Data Table
Neocortex basket cell Layer 5 somatosensory cortex Fast Spiking parvalbumin positive interneurons resting membrane potential (mV) -67.4 ± 1.5 (8) -67.4 (mV) Data Table
Neocortex basket cell Layer 5 somatosensory cortex Fast Spiking parvalbumin positive interneurons sag amplitude (mV) 1.17 ± 0.3 (8) 1.17 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex small amplitude pyramidal cells adaptation percent (1 – first/last ISI) 20.3 ± 4.8 (10) 20.3 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex large amplitude pyramidal cells adaptation percent (1 – first/last ISI) 18.5 ± 3.1 (9) 18.5 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex large amplitude pyramidal cells cell capacitance (pF) 125.5 ± 22.3 (9) 125.5 (pF) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex small amplitude pyramidal cells cell capacitance (pF) 116.9 ± 13.5 (10) 116.9 (pF) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex large amplitude pyramidal cells FI slope 7.4 ± 0.2 (9) 7.4 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex small amplitude pyramidal cells FI slope 7.0 ± 0.4 (10) 7.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex large amplitude pyramidal cells firing frequency (Hz) 14.8 ± 2.6 (9) 14.8 (Hz) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex small amplitude pyramidal cells firing frequency (Hz) 14.1 ± 3.0 (10) 14.1 (Hz) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex small amplitude pyramidal cells input resistance 116.6 ± 15.8 (10) 116.6 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex large amplitude pyramidal cells input resistance 119.7 ± 19.5 (9) 119.7 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex small amplitude pyramidal cells medium AHP amplitude (mV) 3.72 ± 0.7 (10) 3.72 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex large amplitude pyramidal cells medium AHP amplitude (mV) 4.32 ± 0.8 (9) 4.32 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex small amplitude pyramidal cells resting membrane potential (mV) -62.0 ± 1.3 (10) -62.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex large amplitude pyramidal cells resting membrane potential (mV) -64.1 ± 0.9 (9) -64.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex large amplitude pyramidal cells sag amplitude (mV) 4.3 ± 0.8 (9) 4.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Layer 5 somatosensory cortex small amplitude pyramidal cells sag amplitude (mV) 4.35 ± 0.8 (10) 4.35 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
RecTemp 32.0
AnimalAge 13.0 - 24.0
Strain Sprague-Dawley
PrepType in vitro
ElectrodeType Patch-clamp
Species Rats
JxnPotential Not corrected
JxnOffset 10.0
InternalSolution 5.0
ExternalSolution 5.0
Species Mice
internal_0_pH 7.3
internal_0_Mg 2.0
internal_0_Na 2.0
internal_0_K 140.0
internal_0_EGTA 10.0
internal_0_HEPES 10.0
internal_0_Cl 76.0
external_0_pH 7.4
external_0_Mg 2.0
external_0_Na 153.25
external_0_K 2.5
external_0_Cl 132.5
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
8365 Differential effects of Na+-K+ ATPase blockade on cortical layer V neurons. Anderson TR; Huguenard JR; Prince DA J. Physiol. (Lond.) 2010 False 8 Shreejoy Tripathy, Brenna Li, Nathalie Binnion, Patrick Savage, 4