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Article: Altered purinergic signaling in colorectal dorsal root ganglion neurons contributes to colorectal hypersensitivity.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Shinoda M; La JH; Bielefeldt K; Gebhart GF
J. Neurophysiol., 2010

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Dorsal root ganglion cell thoracolumbar colorectal dorsal root ganglion cell access resistance (mohm) 6.0 ± 0.3 6e-09 (MΩ) Data Table
Dorsal root ganglion cell lumbosacral colorectal dorsal root ganglion cell access resistance (mohm) 6.5 ± 0.3 6.5e-09 (MΩ) Data Table
Dorsal root ganglion cell thoracolumbar colorectal dorsal root ganglion cell cell capacitance (pF) 33.0 ± 1.7 33.0 (pF) Data Table
Dorsal root ganglion cell lumbosacral colorectal dorsal root ganglion cell cell capacitance (pF) 33.5 ± 1.3 33.5 (pF) Data Table
Dorsal root ganglion cell thoracolumbar colorectal dorsal root ganglion cell input resistance (mohm) -32.4 ± 3.6 -- Data Table
Dorsal root ganglion cell lumbosacral colorectal dorsal root ganglion cell input resistance (mohm) -40.1 ± 3.3 -- Data Table
Dorsal root ganglion cell thoracolumbar colorectal dorsal root ganglion cell resting membrane potential (mV) -63.5 ± 1.4 -63.5 (mV) Data Table
Dorsal root ganglion cell lumbosacral colorectal dorsal root ganglion cell resting membrane potential (mV) -64.3 ± 1.4 -64.3 (mV) Data Table
Dorsal root ganglion cell lumbosacral colorectal dorsal root ganglion cell rheobase (pA) 227.1 ± 21.7 227.1 (pA) Data Table
Dorsal root ganglion cell thoracolumbar colorectal dorsal root ganglion cell rheobase (pA) 247.3 ± 13.0 247.3 (pA) Data Table
Dorsal root ganglion cell lumbosacral colorectal dorsal root ganglion cell spike threshold (mV) -28.9 ± 1.2 -28.9 (mV) Data Table
Dorsal root ganglion cell thoracolumbar colorectal dorsal root ganglion cell spike threshold (mV) -27.6 ± 1.2 -27.6 (mV) Data Table

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Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
Strain C57BL
PrepType cell culture
RecTemp 21.0 - 23.0
ExternalSolution 5.0
InternalSolution 5.0
JxnPotential Unreported
AnimalWeight 20.0 - 30.0
internal_0_pH 7.25
internal_0_Mg 2.0
internal_0_Na 4.5
internal_0_K 130.0
internal_0_ATP 2.0
internal_0_EGTA 10.0
internal_0_HEPES 10.0
internal_0_Cl 134.4
internal_0_Ca 0.2
external_0_pH 7.4
external_0_Mg 1.0
external_0_Na 140.0
external_0_K 5.0
external_0_HEPES 10.0
external_0_Cl 151.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
109 Altered purinergic signaling in colorectal dorsal root ganglion neurons contributes to colorectal hypersensitivity. Shinoda M; La JH; Bielefeldt K; Gebhart GF J. Neurophysiol. 2010 False 6 Shreejoy Tripathy, Kerrie Tsigounis, Ryan Sefidpour, 4
108 Altered purinergic signaling in colorectal dorsal root ganglion neurons contributes to colorectal hypersensitivity. Shinoda M; La JH; Bielefeldt K; Gebhart GF J. Neurophysiol. 2010 False 0 None
110 Altered purinergic signaling in colorectal dorsal root ganglion neurons contributes to colorectal hypersensitivity. Shinoda M; La JH; Bielefeldt K; Gebhart GF J. Neurophysiol. 2010 False 0 None
111 Altered purinergic signaling in colorectal dorsal root ganglion neurons contributes to colorectal hypersensitivity. Shinoda M; La JH; Bielefeldt K; Gebhart GF J. Neurophysiol. 2010 False 0 None