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Article: Layer V neurons in mouse cortex projecting to different targets have distinct physiological properties.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Hattox AM; Nelson SB
J. Neurophysiol., 2007

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticostriatal projecting slender tufted pyramidal neurons adaptation ratio 0.33 ± 0.03 (28) 0.33 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticotrigeminal projecting pyramidal thick tufted neurons adaptation ratio 0.96 ± 0.05 (19) 0.96 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticocallosal projecting slender tufted pyramidal neurons adaptation ratio 0.43 ± 0.05 (16) 0.43 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticothalamic projecting thick tufted pyramidal neurons adaptation ratio 0.96 ± 0.03 (18) 0.96 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticocallosal projecting slender tufted pyramidal neurons ADP amplitude (mV) 0.0 -- Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticothalamic projecting thick tufted pyramidal neurons ADP amplitude (mV) 7.2 ± 0.8 (18) 7.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticostriatal projecting slender tufted pyramidal neurons ADP amplitude (mV) 1.2 ± 0.4 (28) 1.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticotrigeminal projecting pyramidal thick tufted neurons ADP amplitude (mV) 2.3 ± 0.4 (19) 2.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticostriatal projecting slender tufted pyramidal neurons fast AHP amplitude (mV) 1.5 ± 0.5 (28) 1.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticotrigeminal projecting pyramidal thick tufted neurons fast AHP amplitude (mV) 3.6 ± 0.8 (19) 3.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticocallosal projecting slender tufted pyramidal neurons fast AHP amplitude (mV) 0.1 ± 0.1 (16) 0.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticothalamic projecting thick tufted pyramidal neurons fast AHP amplitude (mV) 7.0 ± 1.0 (18) 7.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticotrigeminal projecting pyramidal thick tufted neurons FI slope 293.0 ± 24.2 (19) 293.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticocallosal projecting slender tufted pyramidal neurons FI slope 154.9 ± 14.1 (16) 154.9 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticothalamic projecting thick tufted pyramidal neurons FI slope 276.8 ± 17.9 (18) 276.8 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticostriatal projecting slender tufted pyramidal neurons FI slope 152.4 ± 18.0 (28) 152.4 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticotrigeminal projecting pyramidal thick tufted neurons input resistance 143.3 ± 6.7 (19) 143.3 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticostriatal projecting slender tufted pyramidal neurons input resistance 183.1 ± 13.3 (28) 183.1 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticothalamic projecting thick tufted pyramidal neurons input resistance 149.8 ± 5.2 (18) 149.8 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticocallosal projecting slender tufted pyramidal neurons input resistance 157.9 ± 10.2 (16) 157.9 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticotrigeminal projecting pyramidal thick tufted neurons resting membrane potential (mV) -63.6 ± 0.6 (19) -63.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticocallosal projecting slender tufted pyramidal neurons resting membrane potential (mV) -67.1 ± 0.7 (16) -67.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticothalamic projecting thick tufted pyramidal neurons resting membrane potential (mV) -62.3 ± 0.4 (18) -62.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticostriatal projecting slender tufted pyramidal neurons resting membrane potential (mV) -67.1 ± 0.6 (28) -67.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticotrigeminal projecting pyramidal thick tufted neurons spike half-width (ms) 1.02 ± 0.05 (19) 1.02 (ms) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticocallosal projecting slender tufted pyramidal neurons spike half-width (ms) 1.11 ± 0.02 (16) 1.11 (ms) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticothalamic projecting thick tufted pyramidal neurons spike half-width (ms) 0.91 ± 0.03 (18) 0.91 (ms) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticostriatal projecting slender tufted pyramidal neurons spike half-width (ms) 1.17 ± 0.02 (28) 1.17 (ms) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticothalamic projecting thick tufted pyramidal neurons spike threshold (mV) -42.3 ± 0.5 (18) -42.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticostriatal projecting slender tufted pyramidal neurons spike threshold (mV) -35.5 ± 0.5 (28) -35.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticotrigeminal projecting pyramidal thick tufted neurons spike threshold (mV) -39.4 ± 0.6 (19) -39.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary somatosensory cortex layer 5 corticocallosal projecting slender tufted pyramidal neurons spike threshold (mV) -36.5 ± 0.7 (16) -36.5 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
Strain C57BL
PrepType in vitro
JxnPotential Not corrected
AnimalAge 23.0 - 28.0
RecTemp 37.0
InternalSolution 5.0
ExternalSolution 5.0
internal_0_Mg 4.0
internal_0_Na 10.3
internal_0_K 120.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_HEPES 10.0
internal_0_Cl 20.0
external_0_Mg 2.0
external_0_Na 152.0
external_0_K 3.0
external_0_Cl 133.0
external_0_Ca 2.0
external_0_glucose 10.0
external_0_picro 50.0
external_0_DNQX 3.0
external_0_BIC 20.0
external_0_DAPV 2.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
339 Layer V neurons in mouse cortex projecting to different targets have distinct physiological properties. Hattox AM; Nelson SB J. Neurophysiol. 2007 False 8 Shreejoy Tripathy, Brenna Li, James liu, Patrick Savage, 3