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Article: Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Tsunematsu T; Kilduff TS; Boyden ES; Takahashi S; Tominaga M; Yamanaka A
J. Neurosci., 2011

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Other lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron cell capacitance (pF) 27.1 ± 1.5 (9) 27.1 (pF) Data Table
Other Lateral hypothalamic area EGFP-expressing orexin-expressing neuron cell capacitance (pF) 27.2 ± 2.0 (11) 27.2 (pF) Data Table
Other lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron input resistance (MΩ) 531.2 ± 76.7 (7) 531.2 (MΩ) Data Table
Other Lateral hypothalamic area EGFP-expressing orexin-expressing neuron input resistance (MΩ) 489.3 ± 30.2 (12) 489.3 (MΩ) Data Table
Other lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron resting membrane potential (mV) -52.8 ± 2.1 (5) -52.8 (mV) Data Table
Other Lateral hypothalamic area EGFP-expressing orexin-expressing neuron resting membrane potential (mV) -52.5 ± 1.7 (6) -52.5 (mV) Data Table
Other Lateral hypothalamic area EGFP-expressing orexin-expressing neuron spike peak (mV) 13.4 ± 3.0 (5) 13.4 (mV) Data Table
Other lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron spike peak (mV) 17.3 ± 1.6 (6) 17.3 (mV) Data Table
Other Lateral hypothalamic area EGFP-expressing orexin-expressing neuron spontaneous firing rate (Hz) 4.7 ± 1.0 (8) 4.7 (Hz) Data Table
Other lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron spontaneous firing rate (Hz) 4.8 ± 1.0 (5) 4.8 (Hz) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
InternalSolution 5.0
ExternalSolution 5.0
Strain Mice, Transgenic
JxnPotential Corrected
AnimalAge 21.0 - 28.0
RecTemp 24.0 - 26.0
JxnOffset 16.0
internal_0_pH 7.3
internal_0_Mg 2.0
internal_0_Na 9.2
internal_0_K 138.0
internal_0_GTP 0.5
internal_0_ATP 2.0
internal_0_EGTA 0.2
internal_0_HEPES 10.0
internal_0_Cl 8.0
external_0_pH 7.4
external_0_Mg 1.0
external_0_Na 135.0
external_0_K 5.0
external_0_HEPES 10.0
external_0_Cl 144.0
external_0_Ca 1.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
1589 Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice. Tsunematsu T; Kilduff TS; Boyden ES; Takahashi S; Tominaga M; Yamanaka A J. Neurosci. 2011 False 5 Shreejoy Tripathy, Kerrie Tsigounis, 1
1590 Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice. Tsunematsu T; Kilduff TS; Boyden ES; Takahashi S; Tominaga M; Yamanaka A J. Neurosci. 2011 False 0 None
1591 Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice. Tsunematsu T; Kilduff TS; Boyden ES; Takahashi S; Tominaga M; Yamanaka A J. Neurosci. 2011 False 0 None