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Article: Reduction of an afterhyperpolarization current increases excitability in striatal cholinergic interneurons in rat parkinsonism.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Sanchez G; Rodriguez MJ; Pomata P; Rela L; Murer MG J. Neurosci., 2011
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Neostriatum cholinergic cell | Dorsolateral striatum cholinergic motor interneuron | medium AHP amplitude (mV) | 17.9 ± 1.4 (63) | 17.9 (mV) | Data Table |
| Neostriatum cholinergic cell | Dorsolateral striatum cholinergic motor interneuron | spike amplitude (mV) | 79.4 ± 3.0 (63) | 79.4 (mV) | Data Table |
| Neostriatum cholinergic cell | Dorsolateral striatum cholinergic motor interneuron | spike half-width (ms) | 0.45 ± 0.01 (63) | 0.45 (ms) | Data Table |
| Neostriatum cholinergic cell | Dorsolateral striatum cholinergic motor interneuron | spike max rise slope (mV/ms) | 218.0 ± 13.8 (63) | 218.0 (mV/ms) | Data Table |
| Neostriatum cholinergic cell | Dorsolateral striatum cholinergic motor interneuron | spike threshold (mV) | -41.1 ± 1.6 (63) | -41.1 (mV) | Data Table |
Metadata values
| Experimental condition | Value |
|---|---|
| Species | Rats |
| PrepType | in vitro |
| Strain | Sprague-Dawley |
| RecTemp | 34.0 |
| AnimalAge | 84.0 - 105.0 |
| AnimalWeight | 421.0 ± 8.0 |
| JxnPotential | Not corrected |
| ElectrodeType | Patch-clamp |
| InternalSolution | 5.0 |
| ExternalSolution | 5.0 |
| internal_0_Mg | 2.0 |
| internal_0_Na | 6.3 |
| internal_0_K | 140.0 |
| internal_0_GTP | 0.3 |
| internal_0_ATP | 3.0 |
| internal_0_EGTA | 0.1 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 24.0 |
| external_0_Mg | 1.0 |
| external_0_Na | 152.3 |
| external_0_K | 2.5 |
| external_0_Cl | 133.5 |
| external_0_Ca | 2.0 |
| external_0_glucose | 10.0 |
Data table listing
| Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
|---|---|---|---|---|---|---|---|---|
| 1632 | Reduction of an afterhyperpolarization current increases excitability in striatal cholinergic interneurons in rat parkinsonism. | Sanchez G; Rodriguez MJ; Pomata P; Rela L; Murer MG | J. Neurosci. | 2011 | False | 5 | Shreejoy Tripathy, Nathalie Binnion, Ellie Hogan, | 4 |