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Article: Alterations in cortical excitation and inhibition in genetic mouse models of Huntington's disease.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Cummings DM; André VM; Uzgil BO; Gee SM; Fisher YE; Cepeda C; Levine MS
J. Neurosci., 2009

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 2-3 cell capacitance (pF) 145.0 ± 13.0 (11) 145.0 (pF) Data Table
Neocortex pyramidal cell layer 2-3 cell capacitance (pF) 122.0 ± 7.0 (19) 122.0 (pF) Data Table
Neocortex pyramidal cell layer 2-3 cell capacitance (pF) 107.0 ± 6.0 (28) 107.0 (pF) Data Table
Neocortex pyramidal cell layer 2-3 cell capacitance (pF) 150.0 ± 7.0 (35) 150.0 (pF) Data Table
Neocortex pyramidal cell layer 2-3 input resistance (MΩ) 135.0 ± 23.0 (11) 135.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 input resistance (MΩ) 110.0 ± 5.0 (35) 110.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 input resistance (MΩ) 173.0 ± 10.0 (28) 173.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 input resistance (MΩ) 131.0 ± 13.0 (19) 131.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 membrane time constant (ms) 2.6 ± 0.2 (19) 2.6 (ms) Data Table
Neocortex pyramidal cell layer 2-3 membrane time constant (ms) 2.1 ± 0.2 (28) 2.1 (ms) Data Table
Neocortex pyramidal cell layer 2-3 membrane time constant (ms) 2.7 ± 0.1 (35) 2.7 (ms) Data Table
Neocortex pyramidal cell layer 2-3 membrane time constant (ms) 2.2 ± 0.2 (11) 2.2 (ms) Data Table
Neocortex pyramidal cell layer 2-3 resting membrane potential (mV) -73.1 ± 1.6 (11) -73.1 (mV) Data Table
Neocortex pyramidal cell layer 2-3 spike threshold (mV) -44.1 ± 1.7 (11) -44.1 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
PrepType in vitro
ElectrodeType Patch-clamp
Species Mice
RecTemp 20.0 - 24.0
InternalSolution 5.0
internal_1_pH 7.4
internal_1_Mg 2.0
internal_1_Ca 0.1
internal_1_Cl 6.2
internal_1_K 2.0
internal_2_pH 7.4
internal_2_Mg 2.0
internal_2_Ca 1.0
internal_2_Na 140.0
internal_2_Cl 148.0
internal_2_K 2.0
internal_3_pH 7.25
internal_3_Mg 2.0
internal_3_Na 4.4
internal_3_Cl 4.0
ExternalSolution 5.0
JxnPotential Unreported
Strain C57BL
internal_0_pH 7.2
internal_0_Mg 1.0
internal_0_Na 5.0
internal_0_K 130.0
internal_0_GTP 1.0
internal_0_ATP 5.0
internal_0_EGTA 5.0
internal_0_HEPES 10.0
internal_0_Cl 24.5
internal_0_Ca 0.5
external_0_pH 7.2
external_0_Mg 5.0
external_0_Na 157.25
external_0_K 3.0
external_0_Cl 145.0
external_0_Ca 1.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
1935 Alterations in cortical excitation and inhibition in genetic mouse models of Huntington's disease. Cummings DM; André VM; Uzgil BO; Gee SM; Fisher YE; Cepeda C; Levine MS J. Neurosci. 2009 False 5 Shreejoy Tripathy, Brenna Li, Dmitry Tebaykin, 2
1936 Alterations in cortical excitation and inhibition in genetic mouse models of Huntington's disease. Cummings DM; André VM; Uzgil BO; Gee SM; Fisher YE; Cepeda C; Levine MS J. Neurosci. 2009 False 3 Shreejoy Tripathy, 1