NeuroElectro Publications

Article: Reduced inhibition and increased output of layer II neurons in the medial entorhinal cortex in a model of temporal lobe epilepsy.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Kobayashi M; Wen X; Buckmaster PS
J. Neurosci., 2003

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Medial entorhinal cortex layer II stellate cell		ADP amplitude (mV)	6.3 ± 0.9 (18)	6.3 (mV)	Data Table
Medial entorhinal cortex layer II stellate cell		AHP duration (msec)	54.8 ± 5.3 (18)	54.8 (ms)	Data Table
Medial entorhinal cortex layer II stellate cell		fast AHP amplitude from resting (mV)	1.7 ± 1.2 (18)	1.7 (mV)	Data Table
Medial entorhinal cortex layer II stellate cell		FI slope	45.0 ± 4.0 (18)	45.0 (Hz/nA)	Data Table
Medial entorhinal cortex layer II stellate cell		input resistance (MΩ)	96.0 ± 12.0 (18)	96.0 (MΩ)	Data Table
Medial entorhinal cortex layer II stellate cell		medium AHP amplitude from resting (mV)	-1.7 ± 0.2 (18)	1.7 (mV)	Data Table
Medial entorhinal cortex layer II stellate cell		resting membrane potential (mV)	-59.1 ± 0.9 (18)	-59.1 (mV)	Data Table
Medial entorhinal cortex layer II stellate cell		sag ratio	66.0 ± 4.0 (18)	0.66 (ratio)	Data Table
Medial entorhinal cortex layer II stellate cell		spike amplitude from resting (mV)	102.5 ± 2.9 (18)	102.5 (mV)	Data Table
Medial entorhinal cortex layer II stellate cell		spike half-width (msec)	0.9 (18)	0.9 (ms)	Data Table
Medial entorhinal cortex layer II stellate cell		spike threshold (mV)	-46.1 ± 0.7 (18)	-46.1 (mV)	Data Table

Metadata values

Experimental condition	Value
Species	Rats
ElectrodeType	Patch-clamp
PrepType	in vitro
Strain	Sprague-Dawley
RecTemp	30.0 - 31.0
AnimalAge	38.0 - 70.0
JxnPotential	Corrected
InternalSolution	5.0
internal_1_Mg	2.0
internal_1_Na	8.3
internal_1_Cl	8.0
ExternalSolution	5.0
JxnOffset	7.0
internal_0_Mg	5.0
internal_0_Na	4.3
internal_0_K	100.0
internal_0_GTP	0.3
internal_0_ATP	2.0
internal_0_EGTA	10.0
internal_0_HEPES	40.0
internal_0_Cl	10.0
external_0_Mg	2.0
external_0_Na	153.25
external_0_K	3.0
external_0_Cl	133.0
external_0_Ca	2.0
external_0_glucose	10.0

Data table listing

Data Table	Article Title	Authors	Journal	Year	Table needs expert?	Ephys table mentions	Curated by	Times validated
2711	Reduced inhibition and increased output of layer II neurons in the medial entorhinal cortex in a model of temporal lobe epilepsy.	Kobayashi M; Wen X; Buckmaster PS	J. Neurosci.	2003	False	11	Shreejoy Tripathy, Kerrie Tsigounis, James liu, Patrick Savage,	2