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Article: The leaner P/Q-type calcium channel mutation renders cerebellar Purkinje neurons hyper-excitable and eliminates Ca2+-Na+ spike bursts.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Ovsepian SV; Friel DD Eur. J. Neurosci., 2008
Metadata values
| Experimental condition | Value |
|---|---|
| Species | Mice |
| ElectrodeType | Patch-clamp |
| PrepType | in vitro |
| Strain | C57BL |
| Strain | Mouse, Transgenic |
| RecTemp | 32.0 - 34.0 |
| AnimalAge | 16.0 - 21.0 |
| JxnPotential | Not corrected |
| ExternalSolution | 5.0 |
| InternalSolution | 5.0 |
| internal_1_pH | 7.3 |
| internal_1_Mg | 4.6 |
| internal_1_Na | 0.3 |
| internal_1_Cl | 139.2 |
| internal_0_pH | 7.3 |
| internal_0_Mg | 2.0 |
| internal_0_Na | 5.0 |
| internal_0_K | 150.0 |
| internal_0_ATP | 2.0 |
| internal_0_EGTA | 0.01 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 15.0 |
| external_0_Mg | 2.0 |
| external_0_Na | 151.25 |
| external_0_K | 2.5 |
| external_0_Cl | 135.5 |
| external_0_Ca | 2.0 |
| external_0_Cs | 33.0 |
| external_0_glucose | 25.0 |