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Article: Retrograde viral vector-mediated inhibition of pontospinal noradrenergic neurons causes hyperalgesia in rats.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Howorth PW; Thornton SR; O'Brien V; Smith WD; Nikiforova N; Teschemacher AG; Pickering AE
J. Neurosci., 2009

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Locus coeruleus noradrenergic neuron AHP amplitude (mV) 23.0 (18) 23.0 (mV) Data Table
Locus coeruleus noradrenergic neuron AHP duration (ms) 124.0 (18) 124.0 (ms) Data Table
Locus coeruleus noradrenergic neuron input resistance (MΩ) 327.0 ± 14.0 (18) 327.0 (MΩ) Data Table
Locus coeruleus noradrenergic neuron resting membrane potential (mV) -58.5 (18) -58.5 (mV) Data Table
Locus coeruleus noradrenergic neuron spike amplitude (mV) 60.0 ± 3.0 (18) 60.0 (mV) Data Table
Locus coeruleus noradrenergic neuron spike threshold (mV) -37.0 ± 1.4 (18) -37.0 (mV) Data Table
Locus coeruleus noradrenergic neuron spontaneous firing rate (Hz) 1.0 (18) 1.0 (Hz) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
Strain Wistar
PrepType cell culture
AnimalAge 7.0 - 8.0
RecTemp 20.0
JxnPotential Corrected
ExternalSolution 5.0
InternalSolution 5.0
JxnOffset 13.0
internal_0_Mg 2.0
internal_0_Na 14.4
internal_0_K 140.0
internal_0_GTP 0.2
internal_0_ATP 2.0
internal_0_HEPES 10.0
internal_0_Cl 24.0
external_0_pH 7.3
external_0_Mg 1.25
external_0_Na 149.0
external_0_K 4.25
external_0_Cl 133.0
external_0_Ca 2.5
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
1898 Retrograde viral vector-mediated inhibition of pontospinal noradrenergic neurons causes hyperalgesia in rats. Howorth PW; Thornton SR; O'Brien V; Smith WD; Nikiforova N; Teschemacher AG; Pickering AE J. Neurosci. 2009 False 7 Shreejoy Tripathy, Patrick Savage, Ryan Sefidpour, Athanasios Kritharis, 2
1897 Retrograde viral vector-mediated inhibition of pontospinal noradrenergic neurons causes hyperalgesia in rats. Howorth PW; Thornton SR; O'Brien V; Smith WD; Nikiforova N; Teschemacher AG; Pickering AE J. Neurosci. 2009 False 0 None