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Article: Modulation of hippocampal synaptic transmission by low concentrations of cell-permeant Ca2+ chelators: effects of Ca2+ affinity, chelator structure and binding kinetics.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Spigelman I; Tymianski M; Wallace CM; Carlen PL; Velumian AA
Neuroscience, 1996

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell input resistance (MΩ) 32.7 ± 1.87 (9) 32.7 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 31.6 ± 2.42 (7) 31.6 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 29.4 ± 2.03 (7) 29.4 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 28.5 ± 0.55 (9) 28.5 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 28.8 ± 2.9 (9) 28.8 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 30.6 ± 2.42 (8) 30.6 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 30.8 ± 1.65 (7) 30.8 (MΩ) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 12.0 ± 0.68 (9) 12.0 (ms) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 12.4 ± 0.83 (7) 12.4 (ms) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 12.8 ± 0.69 (7) 12.8 (ms) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 12.8 ± 1.39 (9) 12.8 (ms) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 12.3 ± 0.58 (9) 12.3 (ms) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 12.6 ± 1.22 (8) 12.6 (ms) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 11.3 ± 0.64 (7) 11.3 (ms) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -69.0 ± 2.0 (7) -69.0 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -68.0 ± 1.7 (7) -68.0 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -68.0 ± 1.2 (9) -68.0 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -68.0 ± 1.4 (9) -68.0 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -67.0 ± 1.5 (8) -67.0 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -68.0 ± 2.0 (7) -68.0 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -68.0 ± 1.3 (9) -68.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 105.0 ± 1.6 (7) 105.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 105.0 ± 1.0 (9) 105.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 103.0 ± 1.4 (7) 103.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 106.0 ± 1.5 (7) 106.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 104.0 ± 1.2 (9) 104.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 107.0 ± 0.94 (9) 107.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 103.0 ± 1.4 (8) 103.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.95 ± 0.02 (7) 0.95 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.87 ± 0.03 (7) 0.87 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.94 ± 0.02 (9) 0.94 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.89 ± 0.03 (8) 0.89 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.93 ± 0.02 (9) 0.93 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.97 ± 0.02 (7) 0.97 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.93 ± 0.02 (9) 0.93 (ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (V/s) 483.0 ± 10.6 (9) 483.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (V/s) 480.0 ± 20.0 (7) 480.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (V/s) 498.0 ± 11.8 (7) 498.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (V/s) 468.0 ± 12.2 (9) 468.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (V/s) 494.0 ± 11.8 (9) 494.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (V/s) 502.0 ± 11.3 (8) 502.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (V/s) 499.0 ± 11.1 (7) 499.0 (mV/ms) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
PrepType in vitro
Strain Sprague-Dawley
AnimalAge 30.0 - 36.0
AnimalWeight 180.0 - 240.0
RecTemp 20.0 - 25.0
InternalSolution 5.0
ExternalSolution 5.0
JxnPotential Unreported
internal_0_pH 7.25
internal_0_Mg 2.0
internal_0_Na 10.0
internal_0_K 150.0
internal_0_ATP 2.0
internal_0_EGTA 0.1
internal_0_HEPES 10.0
internal_0_Cl 10.0
external_0_pH 7.4
external_0_Mg 2.0
external_0_Na 152.25
external_0_K 2.5
external_0_Cl 135.5
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
24554 Modulation of hippocampal synaptic transmission by low concentrations of cell-permeant Ca2+ chelators: effects of Ca2+ affinity, chelator structure and binding kinetics. Spigelman I; Tymianski M; Wallace CM; Carlen PL; Velumian AA Neuroscience 1996 False 6 Shreejoy Tripathy, Brenna Li, Dmitry Tebaykin, 2
24553 Modulation of hippocampal synaptic transmission by low concentrations of cell-permeant Ca2+ chelators: effects of Ca2+ affinity, chelator structure and binding kinetics. Spigelman I; Tymianski M; Wallace CM; Carlen PL; Velumian AA Neuroscience 1996 False 0 None