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Article: Loss of mTOR repressors Tsc1 or Pten has divergent effects on excitatory and inhibitory synaptic transmission in single hippocampal neuron cultures.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Weston MC; Chen H; Swann JW
Front Mol Neurosci, 2014

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Other Glutamatergic hippocampal autaptic neuron cell capacitance (pF) 81.3 ± 5.7 (32) 81.3 (pF) Data Table
Other Glutamatergic hippocampal autaptic neuron cell capacitance (pF) 79.5 ± 5.7 79.5 (pF) Data Table
Other Glutamatergic hippocampal autaptic neuron input resistance 390.0 ± 36.0 390.0 (MΩ) Data Table
Other Glutamatergic hippocampal autaptic neuron input resistance 438.0 ± 31.0 (32) 438.0 (MΩ) Data Table
Other Glutamatergic hippocampal autaptic neuron membrane time constant (ms) 32.3 ± 2.5 32.3 (ms) Data Table
Other Glutamatergic hippocampal autaptic neuron membrane time constant (ms) 34.2 ± 3.3 (32) 34.2 (ms) Data Table
Other Glutamatergic hippocampal autaptic neuron resting membrane potential -59.7 ± 2.1 -59.7 (mV) Data Table
Other Glutamatergic hippocampal autaptic neuron resting membrane potential -58.0 ± 2.2 (32) -58.0 (mV) Data Table
Other Glutamatergic hippocampal autaptic neuron rheobase (pA) 176.0 ± 17.0 (32) 176.0 (pA) Data Table
Other Glutamatergic hippocampal autaptic neuron rheobase (pA) 155.0 ± 13.0 155.0 (pA) Data Table
Other Glutamatergic hippocampal autaptic neuron spike amplitude (mV) 66.7 ± 2.8 66.7 (mV) Data Table
Other Glutamatergic hippocampal autaptic neuron spike amplitude (mV) 88.4 ± 5.2 (32) 88.4 (mV) Data Table
Other Glutamatergic hippocampal autaptic neuron spike half-width (ms) 1.16 ± 0.08 (32) 1.16 (ms) Data Table
Other Glutamatergic hippocampal autaptic neuron spike half-width (ms) 1.26 ± 0.09 1.26 (ms) Data Table
Other Glutamatergic hippocampal autaptic neuron spike threshold (mV) -32.9 ± 1.2 -32.9 (mV) Data Table
Other Glutamatergic hippocampal autaptic neuron spike threshold (mV) -29.1 ± 1.0 (32) -29.1 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
RecTemp 23.0 - 24.0
ExternalSolution 5.0
InternalSolution 5.0
Species Mice
Strain Mice, Transgenic
JxnPotential Unreported
AnimalAge 0.0
Strain C57BL
PrepType cell culture
internal_0_Mg 0.6
internal_0_Na 124.0
internal_0_K 136.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_EGTA 1.0
internal_0_HEPES 17.8
internal_0_Cl 137.2
external_0_pH 7.3
external_0_Mg 4.0
external_0_Na 140.0
external_0_K 2.4
external_0_HEPES 10.0
external_0_Cl 154.4
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
27436 Loss of mTOR repressors Tsc1 or Pten has divergent effects on excitatory and inhibitory synaptic transmission in single hippocampal neuron cultures. Weston MC; Chen H; Swann JW Front Mol Neurosci 2014 False 8 Nathalie Binnion, Brenna Li, Athanasios Kritharis, 2