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Article: Molecular and electrophysiological characterization of GFP-expressing CA1 interneurons in GAD65-GFP mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Wierenga CJ; Müllner FE; Rinke I; Keck T; Stein V; Bonhoeffer T
PLoS ONE, 2010

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons adaptation percent (first/last ISI) 52.0 ± 7.0 (4) 52.0 (ratio) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron adaptation percent (first/last ISI) 55.0 ± 4.0 (12) 55.0 (ratio) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons adaptation percent (first/last ISI) 59.0 ± 7.0 (6) 59.0 (ratio) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron adaptation percent (first/last ISI) 67.0 ± 8.0 (5) 67.0 (ratio) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons adaptation percent (first/last ISI) 65.0 ± 8.0 (5) 65.0 (ratio) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons AHP amplitude (mV) -19.0 ± 2.0 (5) 19.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons AHP amplitude (mV) -17.0 ± 2.0 (4) 17.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron AHP amplitude (mV) -19.0 ± 1.0 (12) 19.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons AHP amplitude (mV) -16.0 ± 2.0 (6) 16.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron AHP amplitude (mV) -22.0 ± 2.0 (5) 22.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons first spike latency (ms) 29.0 ± 73.0 (6) 29.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron first spike latency (ms) 525.0 ± 80.0 (5) 525.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons first spike latency (ms) 70.0 ± 78.0 (5) 70.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons first spike latency (ms) 513.0 ± 68.0 (4) 513.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron first spike latency (ms) 496.0 ± 40.0 (12) 496.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron input resistance (MΩ) 377.0 ± 54.0 (5) 377.0 (MΩ) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons input resistance (MΩ) 372.0 ± 59.0 (5) 372.0 (MΩ) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons input resistance (MΩ) 401.0 ± 50.0 (4) 401.0 (MΩ) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron input resistance (MΩ) 468.0 ± 30.0 (12) 468.0 (MΩ) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons input resistance (MΩ) 253.0 ± 50.0 (6) 253.0 (MΩ) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons maximum firing rate (Hz) 89.0 ± 9.0 (6) 89.0 (Hz) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron maximum firing rate (Hz) 120.0 ± 9.0 (5) 120.0 (Hz) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons maximum firing rate (Hz) 66.0 ± 9.0 (5) 66.0 (Hz) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons maximum firing rate (Hz) 87.0 ± 9.0 (4) 87.0 (Hz) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron maximum firing rate (Hz) 79.0 ± 5.0 (12) 79.0 (Hz) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron membrane time constant (ms) 225.0 ± 20.0 (12) -- Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons membrane time constant (ms) 21.0 ± 12.0 (6) 21.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron membrane time constant (ms) 36.0 ± 13.0 (5) 36.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons membrane time constant (ms) 271.0 ± 32.0 (6) -- Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron membrane time constant (ms) 158.0 ± 35.0 (5) 158.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons membrane time constant (ms) 34.0 ± 14.0 (5) 34.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons membrane time constant (ms) 57.0 ± 12.0 (4) 57.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons membrane time constant (ms) 104.0 ± 39.0 (5) 104.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron membrane time constant (ms) 63.0 ± 7.0 (12) 63.0 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons membrane time constant (ms) 238.0 ± 39.0 (4) -- Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons resting membrane potential (mV) -51.0 ± 2.0 (5) -51.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons resting membrane potential (mV) -55.0 ± 2.0 (4) -55.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron resting membrane potential (mV) -49.0 ± 1.0 (12) -49.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons resting membrane potential (mV) -58.0 ± 2.0 (6) -58.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron resting membrane potential (mV) -51.0 ± 2.0 (5) -51.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons spike amplitude (mV) -76.0 ± 4.0 (4) -- Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron spike amplitude (mV) 78.0 ± 2.0 (12) 78.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons spike amplitude (mV) -80.0 ± 4.0 (6) -- Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron spike amplitude (mV) 75.0 ± 4.0 (5) 75.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons spike amplitude (mV) 65.0 ± 4.0 (5) 65.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons spike threshold (mV) -42.0 ± 2.0 (6) -42.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron spike threshold (mV) -35.0 ± 2.0 (5) -35.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons spike threshold (mV) -35.0 ± 2.0 (5) -35.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons spike threshold (mV) -35.0 ± 2.0 (4) -35.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron spike threshold (mV) -35.0 ± 1.0 (12) -35.0 (mV) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 strongly adapting GABAergic interneurons spike width (ms) 1.6 ± 0.1 (5) 1.6 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting irregular spiking GABAergic interneurons spike width (ms) 1.7 ± 0.1 (4) 1.7 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting regular spiking GABAergic interneuron spike width (ms) 1.6 ± 0.1 (12) 1.6 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 immediate onset, adapting GABAergic interneurons spike width (ms) 1.2 ± 0.1 (6) 1.2 (ms) Data Table
Hippocampus CA1 IS-I neuron Hippocampus CA1 delayed onset, adapting fast spiking GABAergic interneuron spike width (ms) 1.2 ± 0.1 (5) 1.2 (ms) Data Table

Report miscurated data

Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
RecTemp 20.0 - 24.0
PrepType in vitro
AnimalAge 14.0
JxnPotential Not corrected
InternalSolution 5.0
Species Mice
Strain GAD65-GFP
JxnOffset -14.0
ExternalSolution 5.0
internal_0_Mg 4.4
internal_0_Na 4.0
internal_0_K 154.0
internal_0_GTP 0.4
internal_0_ATP 4.0
internal_0_HEPES 10.0
internal_0_Cl 8.0
external_0_Mg 1.43
external_0_Na 160.82
external_0_K 2.75
external_0_Cl 138.65
external_0_Ca 2.5
external_0_glucose 11.1

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
42867 Molecular and electrophysiological characterization of GFP-expressing CA1 interneurons in GAD65-GFP mice. Wierenga CJ; Müllner FE; Rinke I; Keck T; Stein V; Bonhoeffer T PLoS ONE 2010 True 10 Shreejoy Tripathy, Brenna Li, Nathalie Binnion, James liu, Patrick Savage, 2
42866 Molecular and electrophysiological characterization of GFP-expressing CA1 interneurons in GAD65-GFP mice. Wierenga CJ; Müllner FE; Rinke I; Keck T; Stein V; Bonhoeffer T PLoS ONE 2010 False 0 None