AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Kron M; Howell CJ; Adams IT; Ransbottom M; Christian D; Ogier M; Katz DM
J. Neurosci., 2012

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural relay neurons cell capacitance (pF) 24.9 ± 1.3 (49) 24.9 (pF) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural relay neurons input resistance (MΩ) 583.5 ± 45.3 (49) 583.5 (MΩ) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural relay neurons resting membrane potential (mV) -56.1 ± 1.1 (49) -56.1 (mV) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons cell capacitance (pF) 34.6 ± 3.0 (21) 34.6 (pF) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons cell capacitance (pF) 37.8 ± 2.4 (26) 37.8 (pF) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons input resistance (mΩ) 440.6 ± 60.0 (26) 440.6 (MΩ) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons input resistance (mΩ) 447.3 ± 56.3 (21) 447.3 (MΩ) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons resting membrane potential (mV) -60.4 ± 1.8 (21) -60.4 (mV) Data Table
Other lateral nucleus tractus solitarius second-order relay neurons resting membrane potential (mV) -64.5 ± 2.1 (26) -64.5 (mV) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron AHP amplitude (mV) -24.33 ± 1.6 (15) 24.33 (mV) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron spike amplitude (mV) 76.05 ± 2.38 (15) 76.05 (mV) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron spike decay time (ms) 0.7 ± 0.02 (15) 0.7 (ms) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron spike rise time (ms) 0.91 ± 0.04 (15) 0.91 (ms) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron spike threshold (mV) -31.68 ± 1.56 (15) -31.68 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
ExternalSolution 5.0
InternalSolution 5.0
Strain C57BL
Strain BALB C
Strain Other
JxnPotential Unreported
RecTemp 30.0 - 32.0
AnimalAge 35.0 - 49.0
internal_0_Mg 3.0
internal_0_Na 10.2
internal_0_K 130.0
internal_0_GTP 0.2
internal_0_ATP 2.0
internal_0_EGTA 11.0
internal_0_HEPES 10.0
internal_0_Cl 14.0
internal_0_Ca 1.0
external_0_pH 7.4
external_0_Mg 1.2
external_0_Na 151.2
external_0_K 3.0
external_0_Cl 132.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
47215 Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment. Kron M; Howell CJ; Adams IT; Ransbottom M; Christian D; Ogier M; Katz DM J. Neurosci. 2012 False 5 Kerrie Tsigounis, Shreejoy Tripathy, Athanasios Kritharis, 1
47213 Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment. Kron M; Howell CJ; Adams IT; Ransbottom M; Christian D; Ogier M; Katz DM J. Neurosci. 2012 False 3 Kerrie Tsigounis, Athanasios Kritharis, 1
47214 Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment. Kron M; Howell CJ; Adams IT; Ransbottom M; Christian D; Ogier M; Katz DM J. Neurosci. 2012 False 3 Kerrie Tsigounis, Athanasios Kritharis, 1
47216 Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment. Kron M; Howell CJ; Adams IT; Ransbottom M; Christian D; Ogier M; Katz DM J. Neurosci. 2012 False 1 0
47212 Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment. Kron M; Howell CJ; Adams IT; Ransbottom M; Christian D; Ogier M; Katz DM J. Neurosci. 2012 False 0 None
47217 Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment. Kron M; Howell CJ; Adams IT; Ransbottom M; Christian D; Ogier M; Katz DM J. Neurosci. 2012 False 0 None