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Article: Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Gant JC; Chen KC; Kadish I; Blalock EM; Thibault O; Porter NM; Landfield PW
J. Neurosci., 2015

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell input resistance (MΩ) 53.81 ± 2.65 (16) 53.81 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 53.85 ± 3.92 (13) 53.85 (MΩ) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -59.39 ± 0.7 (13) -59.39 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -59.44 ± 0.75 (16) -59.44 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 86.28 ± 1.47 (16) 86.28 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 87.94 ± 2.24 (13) 87.94 (mV) Data Table

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Metadata values

Experimental condition Value
Species Rats
ElectrodeType Sharp
Strain Rats, Transgenic
PrepType in vivo
InternalSolution 5.0
JxnPotential Unreported
RecTemp 20.0 - 24.0
ExternalSolution 5.0
internal_0_K 2000.0
internal_0_HEPES 10.0
external_0_Mg 2.0
external_0_Na 154.0
external_0_K 4.25
external_0_Cl 139.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
47312 Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus. Gant JC; Chen KC; Kadish I; Blalock EM; Thibault O; Porter NM; Landfield PW J. Neurosci. 2015 False 3 Brenna Li, Ryan Sefidpour, 1