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Article: Mice lacking the transcriptional coactivator PGC-1α exhibit alterations in inhibitory synaptic transmission in the motor cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Dougherty SE; Bartley AF; Lucas EK; Hablitz JJ; Dobrunz LE; Cowell RM
Neuroscience, 2014

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex basket cell Motor cortex layer 5 fast spiking parvalbumin positive interneurons AHP amplitude (mV) 17.41 (8) 17.41 (mV) Data Table
Neocortex basket cell Motor cortex layer 5 non fast spiking parvalbumin positive interneurons AHP amplitude (mV) 19.87 (2) 19.87 (mV) Data Table
Neocortex basket cell Motor cortex layer 5 fast spiking parvalbumin positive interneurons input resistance (MΩ) 160.13 (8) 160.13 (MΩ) Data Table
Neocortex basket cell Motor cortex layer 5 non fast spiking parvalbumin positive interneurons input resistance (MΩ) 200.0 (2) 200.0 (MΩ) Data Table
Neocortex basket cell Motor cortex layer 5 non fast spiking parvalbumin positive interneurons maximum firing rate (Hz) 185.37 (2) 185.37 (Hz) Data Table
Neocortex basket cell Motor cortex layer 5 fast spiking parvalbumin positive interneurons maximum firing rate (Hz) 327.98 (8) 327.98 (Hz) Data Table
Neocortex basket cell Motor cortex layer 5 fast spiking parvalbumin positive interneurons resting membrane potential (mV) -56.0 (8) -56.0 (mV) Data Table
Neocortex basket cell Motor cortex layer 5 non fast spiking parvalbumin positive interneurons resting membrane potential (mV) -56.0 (2) -56.0 (mV) Data Table
Neocortex basket cell Motor cortex layer 5 non fast spiking parvalbumin positive interneurons spike amplitude (mV) 64.6 (2) 64.6 (mV) Data Table
Neocortex basket cell Motor cortex layer 5 fast spiking parvalbumin positive interneurons spike amplitude (mV) 54.27 (8) 54.27 (mV) Data Table
Neocortex basket cell Motor cortex layer 5 non fast spiking parvalbumin positive interneurons spike half-width (ms) 0.69 (2) 0.69 (ms) Data Table
Neocortex basket cell Motor cortex layer 5 fast spiking parvalbumin positive interneurons spike half-width (ms) 0.51 (8) 0.51 (ms) Data Table
Neocortex basket cell Motor cortex layer 5 non fast spiking parvalbumin positive interneurons spike threshold (mV) -43.04 (2) -43.04 (mV) Data Table
Neocortex basket cell Motor cortex layer 5 fast spiking parvalbumin positive interneurons spike threshold (mV) -43.63 (8) -43.63 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
AnimalAge 27.0 - 33.0
ExternalSolution 5.0
InternalSolution 5.0
external_1_Mg 1.0
external_1_Ca 2.0
external_1_Na 153.25
external_1_Cl 135.0
external_1_K 3.0
internal_1_Na 13.0
internal_1_Cl 9.0
internal_1_K 156.0
Species Mice
Strain G42
PrepType in vitro
JxnPotential Unreported
RecTemp 22.0
internal_0_pH 7.2
internal_0_Mg 2.0
internal_0_GTP 0.2
internal_0_ATP 2.0
internal_0_EGTA 10.0
internal_0_HEPES 10.0
internal_0_Cl 129.0
internal_0_Cs 129.0
external_0_Mg 2.0
external_0_Na 151.0
external_0_K 3.5
external_0_Cl 136.5
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
47636 Mice lacking the transcriptional coactivator PGC-1α exhibit alterations in inhibitory synaptic transmission in the motor cortex. Dougherty SE; Bartley AF; Lucas EK; Hablitz JJ; Dobrunz LE; Cowell RM Neuroscience 2014 False 7 Shreejoy Tripathy, Nathalie Binnion, 2