AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Fan J; Stemkowski PL; Gandini MA; Black SA; Zhang Z; Souza IA; Chen L; Zamponi GW
Front Cell Neurosci, 2016

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell input resistance 256.0 ± 35.6 (8) 256.0 (MΩ) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -55.0 ± 1.4 (5) -55.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (ms) 107.0 ± 6.6 (5) -- Data Table
Hippocampus CA1 pyramidal cell spike half-width (mV/ms) 1.9 ± 0.2 (5) -- Data Table
Hippocampus CA1 pyramidal cell spike max decay slope (mV) -67.0 ± 6.2 (5) -- Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (mV/ms) 132.0 ± 23.5 (5) 132.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike threshold -42.0 ± 2.0 (5) -42.0 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
RecTemp 20.0 - 24.0
AnimalAge 0.0 - 1.0
InternalSolution 5.0
ExternalSolution 5.0
Species Mice
Strain C57BL
PrepType cell culture
JxnPotential Unreported
internal_0_pH 7.2
internal_0_Mg 4.0
internal_0_Na 0.3
internal_0_K 130.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_EGTA 10.0
internal_0_HEPES 10.0
internal_0_Cl 4.0
internal_0_Ca 2.0
external_0_pH 7.4
external_0_Mg 1.0
external_0_Na 150.0
external_0_K 5.0
external_0_HEPES 10.0
external_0_Cl 162.0
external_0_Ca 2.5
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
49887 Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice. Fan J; Stemkowski PL; Gandini MA; Black SA; Zhang Z; Souza IA; Chen L; Zamponi GW Front Cell Neurosci 2016 False 7 Brenna Li, Ellie Hogan, 1