NeuroElectro Publications

Article: Early exposure to alcohol leads to permanent impairment of dendritic excitability in neocortical pyramidal neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Granato A; Palmer LM; De Giorgio A; Tavian D; Larkum ME
J. Neurosci., 2012

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5b pyramidal cell	fast AHP amplitude (mV)	-7.77 ± 0.43 (19)	7.77 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5b pyramidal cell	input resistance (MΩ)	23.31 ± 1.79 (19)	23.31 (MΩ)	Data Table
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5b pyramidal cell	membrane time constant (ms)	11.43 ± 0.84 (19)	11.43 (ms)	Data Table
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5b pyramidal cell	resting membrane potential (mV)	-72.69 ± 1.01 (19)	-72.69 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5b pyramidal cell	rheobase (pA)	726.32 ± 43.15 (19)	726.32 (pA)	Data Table
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5b pyramidal cell	slow AHP amplitude (mV)	-12.86 ± 0.56 (19)	12.86 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5b pyramidal cell	spike amplitude (mV)	87.46 ± 0.75 (19)	87.46 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5b pyramidal cell	spike half-width (ms)	0.63 ± 0.02 (19)	0.63 (ms)	Data Table
Neocortex pyramidal cell layer 5-6	somatosensory cortex layer 5b pyramidal cell	spike threshold (mV)	-42.56 ± 0.82 (19)	-42.56 (mV)	Data Table

Metadata values

Experimental condition	Value
RecTemp	34.0
AnimalAge	30.0 - 60.0
Strain	Wistar
PrepType	in vitro
ElectrodeType	Patch-clamp
Species	Rats
InternalSolution	5.0
ExternalSolution	5.0
JxnPotential	Unreported
internal_0_pH	7.3
internal_0_Mg	4.0
internal_0_Na	4.3
internal_0_K	135.0
internal_0_GTP	0.3
internal_0_ATP	4.0
internal_0_HEPES	10.0
internal_0_Cl	24.0
external_0_Mg	1.0
external_0_Na	151.25
external_0_K	2.5
external_0_Cl	133.5
external_0_Ca	2.0
external_0_glucose	25.0

Data table listing

Data Table	Article Title	Authors	Journal	Year	Table needs expert?	Ephys table mentions	Curated by	Times validated
1478	Early exposure to alcohol leads to permanent impairment of dendritic excitability in neocortical pyramidal neurons.	Granato A; Palmer LM; De Giorgio A; Tavian D; Larkum ME	J. Neurosci.	2012	False	9	Shreejoy Tripathy,	2