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Article: GABAergic synaptic inhibition is reduced before seizure onset in a genetic model of cortical malformation.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Trotter SA; Kapur J; Anzivino MJ; Lee KS J. Neurosci., 2006
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Neocortex pyramidal cell layer 5-6 | Neocortex layer 5 pyramidal neuron | cell capacitance (pF) | 0.94 ± 0.06 | -- | Data Table |
| Neocortex pyramidal cell layer 5-6 | Neocortex layer 5 pyramidal neuron | input resistance (MΩ) | 56.0 ± 2.3 | 56.0 (MΩ) | Data Table |
| Neocortex pyramidal cell layer 5-6 | Neocortex layer 5 pyramidal neuron | resting membrane potential (mV) | -61.5 ± 0.5 | -61.5 (mV) | Data Table |
Metadata values
| Experimental condition | Value |
|---|---|
| RecTemp | 20.0 - 24.0 |
| AnimalAge | 15.0 |
| Strain | Sprague-Dawley |
| PrepType | in vitro |
| ElectrodeType | Patch-clamp |
| Species | Rats |
| InternalSolution | 5.0 |
| internal_1_pH | 7.4 |
| internal_1_Mg | 4.0 |
| internal_1_Cl | 155.3 |
| ExternalSolution | 5.0 |
| JxnPotential | Unreported |
| internal_0_pH | 7.4 |
| internal_0_Mg | 4.0 |
| internal_0_Na | 2.5 |
| internal_0_K | 142.0 |
| internal_0_ATP | 4.0 |
| internal_0_EGTA | 0.5 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 9.5 |
| external_0_Mg | 1.5 |
| external_0_Na | 152.7 |
| external_0_K | 3.1 |
| external_0_Cl | 132.0 |
| external_0_Ca | 1.5 |
| external_0_glucose | 10.0 |
Data table listing
| Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
|---|---|---|---|---|---|---|---|---|
| 2288 | GABAergic synaptic inhibition is reduced before seizure onset in a genetic model of cortical malformation. | Trotter SA; Kapur J; Anzivino MJ; Lee KS | J. Neurosci. | 2006 | False | 3 | Shreejoy Tripathy, Ryan Sefidpour, | 1 |
| 2289 | GABAergic synaptic inhibition is reduced before seizure onset in a genetic model of cortical malformation. | Trotter SA; Kapur J; Anzivino MJ; Lee KS | J. Neurosci. | 2006 | False | 1 | 0 | |
| 2290 | GABAergic synaptic inhibition is reduced before seizure onset in a genetic model of cortical malformation. | Trotter SA; Kapur J; Anzivino MJ; Lee KS | J. Neurosci. | 2006 | False | 1 | 0 | |
| 2291 | GABAergic synaptic inhibition is reduced before seizure onset in a genetic model of cortical malformation. | Trotter SA; Kapur J; Anzivino MJ; Lee KS | J. Neurosci. | 2006 | False | 1 | 0 |