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Article: Dissociation of dorsal root ganglion neurons induces hyperexcitability that is maintained by increased responsiveness to cAMP and cGMP.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Zheng JH; Walters ET; Song XJ
J. Neurophysiol., 2007

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Dorsal root ganglion cell small dorsal root ganglion AHP amplitude (mV) 21.4 ± 3.5 (22) 21.4 (mV) Data Table
Dorsal root ganglion cell small dorsal root ganglion AHP duration (ms) 13.6 ± 3.5 (22) 13.6 (ms) Data Table
Dorsal root ganglion cell small dorsal root ganglion cell capacitance (pF) 43.2 ± 1.1 (22) 43.2 (pF) Data Table
Dorsal root ganglion cell small dorsal root ganglion cell diameter 20.1 ± 1.6 (22) 20.1 (um) Data Table
Dorsal root ganglion cell small dorsal root ganglion firing frequency 2.05 ± 0.25 (22) 2.05 (Hz) Data Table
Dorsal root ganglion cell small dorsal root ganglion input resistance (MΩ) 416.0 ± 14.0 (22) 416.0 (MΩ) Data Table
Dorsal root ganglion cell small dorsal root ganglion resting membrane potential (mV) -55.9 ± 1.5 (22) -55.9 (mV) Data Table
Dorsal root ganglion cell small dorsal root ganglion rheobase (nA) 0.34 ± 0.04 (22) 340.0 (pA) Data Table
Dorsal root ganglion cell small dorsal root ganglion spike amplitude (mV) 62.1 ± 1.0 (22) 62.1 (mV) Data Table
Dorsal root ganglion cell small dorsal root ganglion spike threshold (mV) -27.2 ± 1.7 (22) -27.2 (mV) Data Table
Dorsal root ganglion cell small dorsal root ganglion spike width (ms) 3.43 ± 0.28 (22) 3.43 (ms) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Rats
Strain Sprague-Dawley
ElectrodeType Patch-clamp
PrepType in vitro
JxnPotential Unreported
AnimalWeight 120.0 - 150.0
RecTemp 22.0
InternalSolution 5.0
ExternalSolution 5.0
internal_0_pH 7.2
internal_0_Mg 4.0
internal_0_K 150.0
internal_0_ATP 2.0
internal_0_HEPES 10.0
internal_0_Cl 26.0
internal_0_Ca 1.0
external_0_pH 7.3
external_0_Mg 1.0
external_0_Na 145.5
external_0_K 3.5
external_0_HEPES 10.0
external_0_Cl 148.5
external_0_Ca 1.5
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
420 Dissociation of dorsal root ganglion neurons induces hyperexcitability that is maintained by increased responsiveness to cAMP and cGMP. Zheng JH; Walters ET; Song XJ J. Neurophysiol. 2007 False 11 Shreejoy Tripathy, Kerrie Tsigounis, Brenna Li, Nathalie Binnion, 2