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Article: BACE1 deficiency causes altered neuronal activity and neurodegeneration.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Hu X; Zhou X; He W; Yang J; Xiong W; Wong P; Wilson CG; Yan R
J. Neurosci., 2010

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell input resistance (MΩ) 400.0 ± 57.0 (11) 400.0 (MΩ) Data Table
Hippocampus CA1 pyramidal cell other (mV) -54.6 ± 2.7 (11) -- Data Table
Hippocampus CA1 pyramidal cell spike amplitude from resting (mV) 90.3 ± 2.4 (11) 90.3 (mV) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 2.36 ± 0.34 (11) 2.36 (ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (mV/ms) 86.3 ± 2.3 (11) 86.3 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -44.1 ± 1.2 (11) -44.1 (mV) Data Table

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Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
RecTemp 20.0 - 24.0
InternalSolution 5.0
internal_1_pH 7.3
internal_1_Mg 1.3
internal_1_Ca 1.8
internal_1_Na 146.9
internal_1_Cl 149.4
internal_1_K 133.0
ExternalSolution 5.0
AnimalAge 21.0 - 30.0
PrepType Other
JxnPotential Unreported
internal_0_pH 7.3
internal_0_Na 6.9
internal_0_K 130.0
internal_0_GTP 0.3
internal_0_ATP 3.0
internal_0_EGTA 0.2
internal_0_HEPES 10.0
external_0_pH 7.4
external_0_Mg 1.3
external_0_Na 140.0
external_0_K 3.0
external_0_HEPES 10.0
external_0_Cl 149.4
external_0_Ca 1.8
external_0_glucose 25.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
1754 BACE1 deficiency causes altered neuronal activity and neurodegeneration. Hu X; Zhou X; He W; Yang J; Xiong W; Wong P; Wilson CG; Yan R J. Neurosci. 2010 False 6 Shreejoy Tripathy, Kerrie Tsigounis, Brenna Li, Ryan Sefidpour, 1
1752 BACE1 deficiency causes altered neuronal activity and neurodegeneration. Hu X; Zhou X; He W; Yang J; Xiong W; Wong P; Wilson CG; Yan R J. Neurosci. 2010 False 2 0
1751 BACE1 deficiency causes altered neuronal activity and neurodegeneration. Hu X; Zhou X; He W; Yang J; Xiong W; Wong P; Wilson CG; Yan R J. Neurosci. 2010 False 0 None
1753 BACE1 deficiency causes altered neuronal activity and neurodegeneration. Hu X; Zhou X; He W; Yang J; Xiong W; Wong P; Wilson CG; Yan R J. Neurosci. 2010 False 0 None