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Article: M1 receptors mediate cholinergic modulation of excitability in neocortical pyramidal neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Gulledge AT; Bucci DJ; Zhang SS; Matsui M; Yeh HH J. Neurosci., 2009
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Neocortex pyramidal cell layer 2-3 | medial prefrontal cortex layer 2-3 pyramidal cell | input resistance (MΩ) | 140.0 ± 30.0 (15) | 140.0 (MΩ) | Data Table |
| Neocortex pyramidal cell layer 2-3 | medial prefrontal cortex layer 2-3 pyramidal cell | resting membrane potential (mV) | -85.0 ± 3.0 (15) | -85.0 (mV) | Data Table |
| Neocortex pyramidal cell layer 2-3 | medial prefrontal cortex layer 2-3 pyramidal cell | sag ratio | 3.0 ± 1.0 (15) | 0.03 (ratio) | Data Table |
| Neocortex pyramidal cell layer 5-6 | medial prefrontal cortex layer 5 pyramidal cell | input resistance (MΩ) | 75.0 ± 33.0 (15) | 75.0 (MΩ) | Data Table |
| Neocortex pyramidal cell layer 5-6 | medial prefrontal cortex layer 5 pyramidal cell | resting membrane potential (mV) | -80.0 ± 2.0 (15) | -80.0 (mV) | Data Table |
| Neocortex pyramidal cell layer 5-6 | medial prefrontal cortex layer 5 pyramidal cell | sag ratio | 15.0 ± 3.0 (15) | 0.15 (ratio) | Data Table |
Metadata values
| Experimental condition | Value |
|---|---|
| Species | Mice |
| ElectrodeType | Patch-clamp |
| PrepType | in vitro |
| Strain | C57BL |
| RecTemp | 35.0 ± 1.0 |
| AnimalAge | 42.0 - 56.0 |
| JxnOffset | 12.0 |
| InternalSolution | 5.0 |
| ExternalSolution | 5.0 |
| JxnPotential | Corrected |
| internal_0_pH | 7.2 |
| internal_0_Mg | 2.0 |
| internal_0_Na | 8.3 |
| internal_0_K | 140.0 |
| internal_0_GTP | 0.3 |
| internal_0_ATP | 3.0 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 6.0 |
| external_0_Mg | 1.0 |
| external_0_Na | 151.25 |
| external_0_K | 3.0 |
| external_0_Cl | 134.0 |
| external_0_Ca | 2.0 |
| external_0_glucose | 25.0 |
Data table listing
| Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
|---|---|---|---|---|---|---|---|---|
| 1939 | M1 receptors mediate cholinergic modulation of excitability in neocortical pyramidal neurons. | Gulledge AT; Bucci DJ; Zhang SS; Matsui M; Yeh HH | J. Neurosci. | 2009 | False | 3 | Shreejoy Tripathy, Brenna Li, Athanasios Kritharis, | 1 |
| 1940 | M1 receptors mediate cholinergic modulation of excitability in neocortical pyramidal neurons. | Gulledge AT; Bucci DJ; Zhang SS; Matsui M; Yeh HH | J. Neurosci. | 2009 | False | 3 | 0 |