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Article: Modulation of neuronal excitability by serotonin-NMDA interactions in prefrontal cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Zhong P; Yuen EY; Yan Z
Mol. Cell. Neurosci., 2008

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Prefrontal Cortex Layer 5 Pyramidal Neurons AHP amplitude (mV) 6.5 ± 0.8 (6) 6.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal Cortex Layer 5 Pyramidal Neurons first spike latency (ms) 71.1 ± 3.9 (6) 71.1 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal Cortex Layer 5 Pyramidal Neurons input resistance 133.7 ± 22.4 (6) 133.7 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal Cortex Layer 5 Pyramidal Neurons resting membrane potential (mV) -71.6 ± 2.1 (6) -71.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal Cortex Layer 5 Pyramidal Neurons rheobase (pA) 121.7 ± 5.6 (6) 121.7 (pA) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal Cortex Layer 5 Pyramidal Neurons spike amplitude (mV) 79.3 ± 3.2 (6) 79.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal Cortex Layer 5 Pyramidal Neurons spike half-width (ms) 2.0 ± 0.2 (6) 2.0 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal Cortex Layer 5 Pyramidal Neurons spike threshold (mV) -52.3 ± 2.6 (6) -52.3 (mV) Data Table

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Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
PrepType in vitro
Strain Sprague-Dawley
InternalSolution 5.0
ExternalSolution 5.0
AnimalAge 21.0 - 28.0
RecTemp 30.0
JxnPotential Unreported
internal_0_pH 7.25
internal_0_Mg 4.0
internal_0_Na 28.6
internal_0_K 120.0
internal_0_GTP 0.2
internal_0_BAPTA 0.5
internal_0_ATP 2.0
internal_0_HEPES 40.0
internal_0_Cl 8.0
external_0_Mg 2.0
external_0_Na 153.25
external_0_K 2.5
external_0_Cl 136.5
external_0_Ca 2.0
external_0_glucose 10.0
external_0_kynur 1.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
23369 Modulation of neuronal excitability by serotonin-NMDA interactions in prefrontal cortex. Zhong P; Yuen EY; Yan Z Mol. Cell. Neurosci. 2008 False 8 Shreejoy Tripathy, Ryan Sefidpour, 6