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Article: Downregulation of Spermine Augments Dendritic Persistent Sodium Currents and Synaptic Integration after Status Epilepticus.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Royeck M; Kelly T; Opitz T; Otte DM; Rennhack A; Woitecki A; Pitsch J; Becker A; Schoch S; Kaupp UB; Yaari Y; Zimmer A; Beck H
J. Neurosci., 2015

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell fast AHP voltage (mV) -49.0 ± 1.0 (9) -49.0 (mV) Data Table
Hippocampus CA1 pyramidal cell firing frequency 30.5 ± 1.3 (9) 30.5 (Hz) Data Table
Hippocampus CA1 pyramidal cell input resistance (mΩ) 113.0 ± 8.0 (9) 113.0 (MΩ) Data Table
Hippocampus CA1 pyramidal cell maximum firing rate (Hz) 48.0 ± 3.0 (9) 48.0 (Hz) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 28.0 ± 3.0 (9) 28.0 (ms) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -75.0 ± 1.0 (9) -75.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 1.14 ± 0.05 (9) 1.14 (ms) Data Table
Hippocampus CA1 pyramidal cell spike max decay slope (V/s) 77.0 ± 3.0 (9) 77.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (V/s) 322.0 ± 15.0 (9) 322.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike peak (mV) 32.0 ± 2.0 (9) 32.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -56.0 ± 1.0 (9) -56.0 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
PrepType in vitro
JxnPotential Corrected
ExternalSolution 5.0
external_1_pH 7.4
external_1_Mg 2.0
external_1_Ca 2.0
external_1_Na 152.25
external_1_Cl 136.5
external_1_K 3.5
external_2_Mg 2.0
external_2_Ca 2.0
external_2_Na 50.0
external_2_Cl 151.9
external_2_K 3.5
InternalSolution 5.0
external_3_pH 7.4
external_3_Mg 1.3
external_3_Ca 2.6
external_3_Na 152.25
external_3_Cl 136.3
external_3_K 3.5
internal_1_Mg 2.0
internal_1_Na 2.0
internal_1_Cl 20.0
internal_1_K 150.0
internal_2_pH 7.4
internal_2_Mg 1.3
internal_2_Ca 2.6
internal_2_Na 140.0
internal_2_Cl 150.8
internal_2_K 3.0
Species Rats
Strain Wistar
AnimalWeight 200.0 - 230.0
RecTemp 32.0
JxnOffset 10.0
internal_0_pH 7.2
internal_0_Mg 2.0
internal_0_Na 2.0
internal_0_K 150.0
internal_0_ATP 4.0
internal_0_EGTA 0.16
internal_0_HEPES 10.0
internal_0_Cl 20.0
internal_0_glucose 15.0
external_0_pH 7.4
external_0_Mg 1.3
external_0_Na 152.25
external_0_K 3.5
external_0_Cl 136.3
external_0_Ca 2.6
external_0_glucose 15.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
47377 Downregulation of Spermine Augments Dendritic Persistent Sodium Currents and Synaptic Integration after Status Epilepticus. Royeck M; Kelly T; Opitz T; Otte DM; Rennhack A; Woitecki A; Pitsch J; Becker A; Schoch S; Kaupp UB; Yaari Y; Zimmer A; Beck H J. Neurosci. 2015 False 11 Shreejoy Tripathy, Brenna Li, Ryan Sefidpour, 2
47376 Downregulation of Spermine Augments Dendritic Persistent Sodium Currents and Synaptic Integration after Status Epilepticus. Royeck M; Kelly T; Opitz T; Otte DM; Rennhack A; Woitecki A; Pitsch J; Becker A; Schoch S; Kaupp UB; Yaari Y; Zimmer A; Beck H J. Neurosci. 2015 False 0 None