Table 3.
Kinetics of desensitizing currents evoked by ATP and protons
| Cluster | Rise Time | Cases | Decay | Rise Time | Cases | Decay |
|---|---|---|---|---|---|---|
| Type 1 | 239.2 ± 33.6* | 6 | 2,300.8 ± 493.1 | n/a | n/a | |
| Type 2 | 173.8 ± 41.2 | 22 | 214.3 ± 48.8 | n/a | n/a | |
| Type 3 | n/a | n/a | 505.3 ± 83.8† | 21 | 683.3 ± 53.4† | |
| Type 4 | 354.9 ± 44.4 | 24 | 2,813.4 ± 404.6 | n/a | n/a | |
| Type 7 | 196.0 ± 36.0 | 8 | 386.0 ± 135.1 | 189.3 ± 36.6 | 8 | 254.9 ± 45.0 |
-
Values are means ± SE. Rise time and decay constants for desensitizing currents evoked by ATP (left) or protons (right). Rise time was determined as the time (ms) between the 1st inward deflection to 90% of the peak current. All decay constants were derived from single exponential fits. * P < 0.05 vs. type 4. † P < 0.02 and P < 0.002 vs. type 7 for rise time and decay, respectively. Doses: ATP, 10 μM; protons, pH 5.0.