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Article: Altered purinergic signaling in colorectal dorsal root ganglion neurons contributes to colorectal hypersensitivity.

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Shinoda M; La JH; Bielefeldt K; Gebhart GF
J. Neurophysiol., 2010


Table 4.

EC50 of ATP and α,β-meATP-produced currents in LS and TL colon neurons fron saline- and zymosan-treated mice

ATP, μM α,β-meATP, μM
Current Treatment logEC50 logEC50
LS
    Fast Saline −4.80 ± 1.31 (53) −4.65 ± 0.45 (41)]P=0.18
Zymosan −5.45 ± 0.28 (36) −5.30 ± 0.19 (42)
    Slow Saline −4.72 ± 0.32 (43) −4.29 ± 0.42 (54)
Zymosan −4.50 ± 1.26 (39) −4.19 ± 0.62 (55)
TL
    Fast Saline −4.47 ± 1.51 (95) −4.65 ± 0.30 (119)]*
Zymosan −5.19 ± 0.50 (90) −5.37 ± 0.09 (153)
    Slow Saline −4.72 ± 0.32 (30) −4.25 ± 0.34 (34)
Zymosan −4.50 ± 1.26 (32) −4.23 ± 0.42 (50)
  • Number of data points for a does-response curve construction are in parentheses.


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Inferred neuron-electrophysiology data values

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