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Article: Modulatory actions of dopamine on NMDA receptor-mediated responses are reduced in D1A-deficient mutant mice.

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Levine MS; Altemus KL; Cepeda C; Cromwell HC; Crawford C; Ariano MA; Drago J; Sibley DR; Westphal H
J. Neurosci., 1996


B. DPSP amplitude, duration, and area

Amplitude (mV) Standard ACSF duration (msec) Area
Control 12.6  ± 1.1 (n  = 28)2_a 12.1  ± 0.7 149  ± 132_b
Mutant 14.6  ± 0.9 (n  = 29) 13.9  ± 1.1 189  ± 13
Mg2+-free ACSF + CNQX
Control 11.5  ± 1.3 (n  = 21) 39.0  ± 3.6 494  ± 96
Mutant 11.7  ± 1.3 (n  = 21) 49.4  ± 4.3 652  ± 118

  • ↵F2_a Mean ± SE. Number for each group is in parentheses.

  • ↵F2_b Difference between means for mutants and controls is statistically significantl (t = −2.11, df = 55,p = 0.0396).


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source