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Article: Dorsoventral Differences in Intrinsic Properties in Developing CA1 Pyramidal Cells.

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Marcelin B; Liu Z; Chen Y; Lewis AS; Becker A; McClelland S; Chetkovich DM; Migliore M; Baram TZ; Esclapez M; Bernard C
J. Neurosci., 2012


Table 3.

Recording distance from the soma (for dendritic recordings) and Ih parameters (current density, V1/2, τ) of dendrites and somata in dorsal and ventral cells for cell attached recordings at PN11–12, as well as for dendrites recorded at PN14–15

Dorsal dendrite PN11–12 (n = 5) Ventral dendrite PN11–12 (n = 6) Dorsal soma PN11–12 (n = 8) Ventral soma PN11–12 (n = 8) Dorsal dendrite PN14–15 (n = 9) Ventral dendrite PN14–15 (n = 7)
Distance (μm) 126 ± 8 145 ± 10 228 ± 10 234 ± 7
Current density (pA/μm2) 4.7 ± 0.3 4.8 ± 1.3 3.8 ± 0.5 1.9 ± 0.5** 9.1 ± 0.8 7.2 ± 0.7*
V1/2 (mV) −97.9 ± 5.6 −101.6 ± 5.3 −99.2 ± 1.8 −109.9 ± 2.7*** −101.6 ± 2.6 −109.9 ± 2.9*
τ (ms) 23.6 ± 1.8 33.4 ± 1.4** 23.6 ± 1.6 35.5 ± 2.2** 21.9 ± 1.9 28.4 ± 2.5*
  • *p < 0.05;

  • **p < 0.01;

  • ***p < 0.001 (ventral vs dorsal).


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