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Article: Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Gant JC; Chen KC; Norris CM; Kadish I; Thibault O; Blalock EM; Porter NM; Landfield PW J. Neurosci., 2011
Table 2.
IHC densitometry data from AAV-injected animals
| contra | ipsi | p value | |
|---|---|---|---|
| Fkbp12.6 | 138.5 ± 3.5 | 115.3 ± 0.9 | 0.0068 |
| mTOR | 83.5 ± 1.9 | 96.0 ± 2.0 | 0.0292 |
| RyR2 | 110.5 ± 2.4 | 131.0 ± 5.9 | 0.0306 |
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shFkbp1b injection resulted after 3–4 weeks in a decrease in FKBP1b and an increase in mTOR and RyR2 immunostaining in the ipsilateral hippocampus. n = 4 sections; paired t test; means ± SEM. contra, Contralateral; ipsi, ipsilateral.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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