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Article: Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.

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Gant JC; Chen KC; Norris CM; Kadish I; Thibault O; Blalock EM; Porter NM; Landfield PW
J. Neurosci., 2011


Table 3.

Basic experimental properties for all recorded CA1 neurons

Control (n = 16) Rapamycin (n = 21)
Input resistance (MΩ) 53.85 ± 6.53 50.31 ± 3.14
Resting membrane potential (mV) −61.67 ± 0.71 −62.83 ± 0.70
Action potential amplitude (mV) 81.43 ± 1.79 82.03 ± 1.53
Electrode resistance (MΩ) 116.11 ± 6.38 112.50 ± 5.45
RSS hyperpolarization (mV) −5.4 ± 0.77 −4.89 ± 0.42
RSS first EPSP (mV) 5.95 ± 1.10 4.55 ± 0.46*
  • No differences were found except in baseline EPSP amplitude.

  • *p < 0.05; means ± SEM.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell input resistance (MΩ) 53.85 ± 6.53 (16) 53.85 (MΩ) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -61.67 ± 0.71 (16) -61.67 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 81.43 ± 1.79 (16) 81.43 (mV) Data Table
Hippocampus CA1 pyramidal cell access resistance (MΩ) 116.11 ± 6.38 (16) -- Data Table