The tested connections were divided according to their RRP size. Note that connections with small RRP (N < 7) and connections with large RRP (N≥ 7) were differentially affected by HD. For abbreviations see list on Introduction page.
Article: Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Dvorzhak A; Semtner M; Faber DS; Grantyn R J. Physiol. (Lond.), 2013
Property | WT | CAR | p value | Test | ||||
---|---|---|---|---|---|---|---|---|
Mean | ±SEM | n | Mean | ±SEM | n | |||
Small N (SON–SON?) | ||||||||
Mean eIPSC amplitude (pA) | 84.04 | 9.18 | 28 | 81.96 | 7.48 | 22 | 0.8665 | Student's unpaired t test |
PPR (eEPSC2/eEPSC1) | 0.74 | 0.03 | 28 | 0.84 | 0.04 | 22 | 0.0823 | Student's unpaired t test |
Pves (mean eIPSC/cumulative eIPSC at time 0) | 0.45 | 0.04 | 28 | 0.33 | 0.03 | 22 | 0.0503 | Student's unpaired t test |
Large N (interneuron–SON?) | ||||||||
Mean eIPSC amplitude (pA) | 205.72 | 20.30 | 29 | 145.23 | 11.37 | 32 | 0.0099 | Student's unpaired t test |
PPR (eEPSC2/eEPSC1) | 0.71 | 0.02 | 29 | 0.82 | 0.03 | 32 | 0.0052 | Student's unpaired t test |
Pves (mean eIPSC/cumulative eIPSC at time 0) | 0.32 | 0.02 | 29 | 0.23 | 0.02 | 32 | 0.0043 | Student's unpaired t test |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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