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Article: Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin.

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Dvorzhak A; Semtner M; Faber DS; Grantyn R
J. Physiol. (Lond.), 2013


Table 4.  Comparison of eIPSCs in R6/2 WT and CAR based on 20 Hz test according to small RRP (N < 7) and large RRP (N≥ 7)
PropertyWTCAR p valueTest
Mean±SEM n Mean±SEM n
 
  1. The tested connections were divided according to their RRP size. Note that connections with small RRP (N < 7) and connections with large RRP (N≥ 7) were differentially affected by HD. For abbreviations see list on Introduction page.

Small N (SON–SON?)
 Mean eIPSC amplitude (pA)84.049.182881.967.48220.8665Student's unpaired t test
 PPR (eEPSC2/eEPSC1)0.740.03280.840.04220.0823Student's unpaired t test
 Pves (mean eIPSC/cumulative eIPSC at time 0)0.450.04280.330.03220.0503Student's unpaired t test
Large N (interneuron–SON?)
 Mean eIPSC amplitude (pA)205.7220.3029145.2311.37320.0099Student's unpaired t test
 PPR (eEPSC2/eEPSC1)0.710.02290.820.03320.0052Student's unpaired t test
 Pves (mean eIPSC/cumulative eIPSC at time 0)0.320.02290.230.02320.0043Student's unpaired t test

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Inferred neuron-electrophysiology data values

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