Article: Functional properties of ES cell-derived neurons engrafted into the hippocampus of adult normal and chronically epileptic rats.
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Rüschenschmidt C; Koch PG; Brüstle O; Beck H
Epilepsia, 2005
Table 1. Passive membrane properties and action potential parameters of embryonic stem cell–derived neurons incorporated into the hippocampus of control and pilocarpine-treated rats in comparison with those of endogenous granule cells Membrane capacitance (pF) Input resistance (GΩ) Threshold (mV) Amplitude (mV) Half-width (ms) Control 47.6 ± 3.6 1.46 ± 0.37 −49.8±1.6 52.6 ± 2.4 2.29 ± 0.19 (n = 13) (n = 10) (n = 9) (n = 9) (n = 9) Pilocarpine-treated 40.0 ± 4.8 1.51 ± 0.38 −51.1 ± 2.5 48.4 ± 2.9 2.74 ± 0.19 (n = 13) (n = 10) (n = 10) (n = 10) (n = 10) Endogenous granule cells control (n = 4) 120.7 ± 10.5 0.248 ± 0.039 –57.0 ± 3.9 107.0 ± 3.1 1.20 ± 0.02 Endogenous granule cells pilocarpine-treated (n = 3) 130.6 ± 19.0 0.308 ± 0.064 –55.3 ± 1.9 104.3 ± 2.4 1.16 ± 0.03
Inferred neuron-electrophysiology data values