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Article: Epilepsy-induced abnormal striatal plasticity in Bassoon mutant mice.

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Ghiglieri V; Picconi B; Sgobio C; Bagetta V; Barone I; Paillè V; Di Filippo M; Polli F; Gardoni F; Altrock W; Gundelfinger ED; De Sarro G; Bernardi G; Ammassari-Teule M; Di Luca M; Calabresi P
Eur. J. Neurosci., 2009


Table 2.   Properties of striatal medium spiny (MS) neurons and fast-spiking (FS) interneurons
 Wild typeBsn mutant
MS, = 25FS, = 19MS, = 24FS, = 20
  1. Values are mean ± SEM of the action potential (AP) half-width, the afterpolarization (AHP) amplitude, the input resistance (Rin), and the resting membrane potential (RMP). No significant differences in these parameters were found between Bsn mutant and wild-type mice for each cell type.

AP half-width (ms)0.62 ± 0.020.57 ± 0.010.60 ± 0.010.55 ± 0.01
AHP amplitude (mV)15.99 ± 0.9821.62 ± 0.5717.97 ± 0.5922.02 ± 0.66
Rin (MΩ)33.87 ± 3.8937.00 ± 4.3735.54 ± 1.8639.64 ± 3.28
RMP (mV)−86.24 ± 4.00−76.91 ± 2.54−85.05 ± 1.45−75.38 ± 1.49

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neostriatum medium spiny neuron input resistance (MΩ) 33.87 ± 3.89 (25) 33.87 (MΩ) Data Table
Neostriatum gabaergic interneuron Neostratium GABAergic fast-spiking interneuron input resistance (MΩ) 37.0 ± 4.37 (19) 37.0 (MΩ) Data Table
Neostriatum medium spiny neuron resting membrane potential (mV) -86.24 ± 4.0 (25) -86.24 (mV) Data Table
Neostriatum gabaergic interneuron Neostratium GABAergic fast-spiking interneuron resting membrane potential (mV) -76.91 ± 2.54 (19) -76.91 (mV) Data Table
Neostriatum medium spiny neuron spike half-width (ms) 0.62 ± 0.02 (25) 0.62 (ms) Data Table
Neostriatum gabaergic interneuron Neostratium GABAergic fast-spiking interneuron spike half-width (ms) 0.57 ± 0.01 (19) 0.57 (ms) Data Table
Neostriatum medium spiny neuron AHP amplitude (mV) 15.99 ± 0.98 (25) 15.99 (mV) Data Table
Neostriatum gabaergic interneuron Neostratium GABAergic fast-spiking interneuron AHP amplitude (mV) 21.62 ± 0.57 (19) 21.62 (mV) Data Table