RMP, resting membrane potential; Vmax, maximal rate of increase of the action potential; fAHP amplitude, the peak amplitude of fast afterhyperpolarization that followed the end of depolarizing current pulses (300 ms, 1.0 nA); Number, number of recording neurons. Data are presented as mean ± SEM.
Article: Seizure, neuron loss, and mossy fiber sprouting in herpes simplex virus type 1-infected organotypic hippocampal cultures.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Chen SF; Huang CC; Wu HM; Chen SH; Liang YC; Hsu KS Epilepsia, 2004
Parameters | Control Regular | 3 DPI (Group I) | 3 DPI (Group II) | 3 DPI (Group III) | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Regular | Grade I | Grade II | Regular | Grade I | Grade II | Regular | Grade II | |||
| ||||||||||
RMP (mV) | −71.8 ± 1.4 | −69.9 ± 2.5 | −61.7 ± 2.2a | −60.8 ± 1.7a | −72.3 ± 1.9 | −60.8 ± 2.3a | −62.9 ± 2.7a | −71.2 ± 2.3 | −60.8 ± 2.3a | −62.9 ± 2.7a |
Input resistance (MΩ) | 70.4 ± 3.1 | 71.8 ± 2.3 | 83.7 ± 2.3a | 83.5 ± 2.8a | 72.8 ± 1.5 | 86.7 ± 2.1a | 79.5 ± 2.9a | 74.8 ± 2.5 | 82.3 ± 2.4a | 84.6 ± 2.7a |
Spike threshold (mV) | −56.2 ± 1.7 | −56.8 ± 1.4 | −55.8 ± 1.4 | −54.2 ± 1.6 | −55.8 ± 2.4 | −54.8 ± 1.3 | −56.2 ± 1.2 | −56.2 ± 2.3 | −55.4 ± 1.8 | −53.8 ± 2.7 |
Spike amplitude (mV) | 81.3 ± 1.6 | 81.8 ± 1.3 | 79.6 ± 2.1 | 78.9 ± 1.9 | 80.9 ± 1.9 | 81.6 ± 1.6 | 80.9 ± 1.3 | 82.1 ± 1.8 | 82.5 ± 1.9 | 82.1 ± 1.8 |
Vmax (mV/ms) | 236.4 ± 14.7 | 231.8 ± 12.4 | 224.3 ± 12.6 | 233.6 ± 16.8 | 228.8 ± 16.3 | 221.3 ± 15.6 | 225.6 ± 9.2 | 227.4 ± 18.3 | 225.2 ± 16.6 | 219.6 ± 14.2 |
fAHP amplitude (mV) | 10.7 ± 2.1 | 9.8 ± 2.8 | 5.2 ± 2.1a | 4.2 ± 1.9a | 10.2 ± 2.6 | 5.3 ± 2.4a | 4.9 ± 1.6a | 11.2 ± 2.3 | 5.8 ± 2.3a | 5.2 ± 2.4a |
Number | 17 | 3 | 10 | 7 | 7 | 8 | 2 | 4 | 8 | 3 |