Cluster 1 corresponds to RS cells in layers II/III (RS sup); cluster 2 corresponds to intrinsic bursting neurons (IB) with soma location in layer IV; clusters 3.1 and 3.2 correspond to subpopulations of RS neurons in layer V/VI (RS deep-1 and RS deep-2). Electrophysiological and morphological parameters used for cluster analysis are given for each of the four main clusters.
Article: Cellular neuroanatomy of rat presubiculum.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Simonnet J; Eugène E; Cohen I; Miles R; Fricker D Eur. J. Neurosci., 2013
Clusters | 1 – RS sup | 2 – IB | 3.1 – RS deep 1 | 3.2 – RS deep 2 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean | SEM | n | Mean | SEM | n | Mean | SEM | n | Mean | SEM | n | |
Lateral position (normalized coordinates) | 0.40 | 0.03 | 24 | 0.36 | 0.04 | 6 | 0.39 | 0.03 | 17 | 0.39 | 0.06 | 11 |
Cell depth (normalized coordinates) | 0.39 | 0.02 | 24 | 0.59 | 0.02 | 6 | 0.82 | 0.02 | 17 | 0.72 | 0.04 | 11 |
Resting membrane potential (mV) | −77.5 | 0.8 | 24 | −62.1 | 1.4 | 6 | −71.1 | 1.3 | 17 | −67.9 | 1.6 | 11 |
Neuronal input resistance (MΩ) | 360 | 24 | 24 | 216 | 28 | 6 | 415 | 32 | 17 | 819 | 67 | 11 |
Tau (ms) | 22 | 1 | 24 | 18 | 2 | 6 | 26 | 3 | 17 | 52 | 7 | 11 |
Sag ratio | 1.06 | 0.01 | 24 | 1.23 | 0.03 | 6 | 1.18 | 0.03 | 17 | 1.10 | 0.02 | 11 |
Rheobase (pA) | 37 | 2 | 24 | 43 | 8 | 6 | 36 | 4 | 17 | 15 | 1 | 11 |
Firing rate at 100 pA (Hz) | 27 | 1 | 24 | 68 | 22 | 6 | 24 | 2 | 17 | 33 | 1 | 11 |
Input–output slope (Hz/nA) | 463 | 24 | 24 | 346 | 196 | 6 | 371 | 23 | 17 | 514 | 27 | 11 |
Bursting Index | 0.18 | 0.02 | 24 | 0.88 | 0.04 | 6 | 0.32 | 0.06 | 17 | 0.19 | 0.05 | 11 |
AP width (ms) | 0.80 | 0.03 | 24 | 0.89 | 0.05 | 6 | 0.95 | 0.05 | 17 | 1.24 | 0.10 | 11 |
AP AHP (mV) | −12.7 | 0.4 | 24 | −14.8 | 1.7 | 6 | −14.6 | 0.8 | 17 | −14.2 | 0.8 | 11 |
AP rise amplitude (mV) | 98.1 | 1.0 | 24 | 89.8 | 3.5 | 6 | 92.7 | 1.5 | 17 | 94.4 | 1.7 | 11 |
AP maximum depolarization rate (V/s) | 506 | 19 | 24 | 359 | 26 | 6 | 367 | 16 | 17 | 340 | 24 | 11 |
AP maximum repolarization rate (V/s) | −122 | 5 | 24 | −91 | 7 | 6 | −97 | 5 | 17 | −80 | 6 | 11 |
AP first AHP (mV) | −11.6 | 0.5 | 24 | 2.8 | 1.2 | 6 | −13.7 | 0.9 | 17 | −13.8 | 0.8 | 11 |
Dendritic count | 4.5 | 0.3 | 24 | 5.3 | 0.6 | 6 | 5.4 | 0.4 | 17 | 3.9 | 0.4 | 11 |
Dendritic length (μm) | 3175 | 171 | 24 | 3357 | 416 | 6 | 3861 | 263 | 17 | 3166 | 295 | 11 |
Layer I dendritic length (μm) | 1340 | 108 | 24 | 1056 | 311 | 6 | 239 | 151 | 17 | 510 | 106 | 11 |
Layer II dendritic length (μm) | 254 | 48 | 24 | 258 | 28 | 6 | 102 | 63 | 17 | 161 | 34 | 11 |
Layer III dendritic length (μm) | 1481 | 139 | 24 | 558 | 171 | 6 | 224 | 63 | 17 | 602 | 133 | 11 |
Layer IV dendritic length (μm) | 87 | 30 | 24 | 1167 | 100 | 6 | 239 | 80 | 17 | 355 | 117 | 11 |
Layer V/VI dendritic length (μm) | 0 | 0 | 24 | 266 | 109 | 6 | 2631 | 208 | 17 | 1775 | 227 | 11 |
0° wedge dendritic length (μm) | 1532 | 107 | 24 | 1762 | 267 | 6 | 748 | 132 | 17 | 1208 | 242 | 11 |
60° wedge dendritic length (μm) | 276 | 59 | 24 | 383 | 171 | 6 | 695 | 200 | 17 | 396 | 150 | 11 |
120° wedge dendritic length (μm) | 216 | 32 | 24 | 309 | 73 | 6 | 525 | 132 | 17 | 302 | 91 | 11 |
180° wedge dendritic length (μm) | 442 | 59 | 24 | 327 | 66 | 6 | 906 | 115 | 17 | 428 | 72 | 11 |
240° wedge dendritic length (μm) | 451 | 60 | 24 | 311 | 40 | 6 | 484 | 90 | 17 | 564 | 129 | 11 |
300° wedge dendritic length (μm) | 281 | 58 | 24 | 292 | 42 | 6 | 535 | 52 | 17 | 283 | 76 | 11 |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Other | presubiculum regular spiking pyramidal cells in layer V/VI | firing frequency (Hz) | 24.0 (17) | 24.0 (Hz) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | firing frequency (Hz) | 33.0 (11) | 33.0 (Hz) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | FI slope (Hz/nA) | 463.0 (24) | 463.0 (Hz/nA) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | FI slope (Hz/nA) | 346.0 (6) | 346.0 (Hz/nA) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | FI slope (Hz/nA) | 371.0 (17) | 371.0 (Hz/nA) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | FI slope (Hz/nA) | 514.0 (11) | 514.0 (Hz/nA) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | other | 0.18 (24) | 0.18 (None) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | other | 0.88 (6) | 0.88 (None) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | other | 0.32 (17) | 0.32 (None) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | other | 0.19 (11) | 0.19 (None) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | spike half-width (ms) | 0.8 (24) | 0.8 (ms) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | spike half-width (ms) | 0.89 (6) | 0.89 (ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | spike half-width (ms) | 0.95 (17) | 0.95 (ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | spike half-width (ms) | 1.24 (11) | 1.24 (ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | AHP amplitude (mV) | -12.7 (24) | 12.7 (mV) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | AHP amplitude (mV) | -14.8 (6) | 14.8 (mV) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | AHP amplitude (mV) | -14.6 (17) | 14.6 (mV) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | AHP amplitude (mV) | -14.2 (11) | 14.2 (mV) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | spike amplitude (mV) | 98.1 (24) | 98.1 (mV) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | spike amplitude (mV) | 89.8 (6) | 89.8 (mV) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | spike amplitude (mV) | 92.7 (17) | 92.7 (mV) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | spike amplitude (mV) | 94.4 (11) | 94.4 (mV) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | spike max rise slope (V/s) | 506.0 (24) | 506.0 (mV/ms) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | spike max rise slope (V/s) | 359.0 (6) | 359.0 (mV/ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | spike max rise slope (V/s) | 367.0 (17) | 367.0 (mV/ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | spike max rise slope (V/s) | 340.0 (11) | 340.0 (mV/ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | spike max decay slope (V/s) | -122.0 (24) | 122.0 (mV/ms) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | spike max decay slope (V/s) | -91.0 (6) | 91.0 (mV/ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | spike max decay slope (V/s) | -97.0 (17) | 97.0 (mV/ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | spike max decay slope (V/s) | -80.0 (11) | 80.0 (mV/ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | resting membrane potential (mV) | -77.5 (24) | -77.5 (mV) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | resting membrane potential (mV) | -62.1 (6) | -62.1 (mV) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | resting membrane potential (mV) | -71.1 (17) | -71.1 (mV) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | resting membrane potential (mV) | -67.9 (11) | -67.9 (mV) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | input resistance (MΩ) | 360.0 (24) | 360.0 (MΩ) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | input resistance (MΩ) | 216.0 (6) | 216.0 (MΩ) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | input resistance (MΩ) | 415.0 (17) | 415.0 (MΩ) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | input resistance (MΩ) | 819.0 (11) | 819.0 (MΩ) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | membrane time constant (ms) | 22.0 (24) | 22.0 (ms) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | membrane time constant (ms) | 18.0 (6) | 18.0 (ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | membrane time constant (ms) | 26.0 (17) | 26.0 (ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | membrane time constant (ms) | 52.0 (11) | 52.0 (ms) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | sag ratio | 1.06 (24) | 1.06 (ratio) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | sag ratio | 1.23 (6) | 1.23 (ratio) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | sag ratio | 1.18 (17) | 1.18 (ratio) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | sag ratio | 1.1 (11) | 1.1 (ratio) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | rheobase (pA) | 37.0 (24) | 37.0 (pA) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | rheobase (pA) | 43.0 (6) | 43.0 (pA) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | rheobase (pA) | 36.0 (17) | 36.0 (pA) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layer V/VI | rheobase (pA) | 15.0 (11) | 15.0 (pA) | Data Table |
Other | presubiculum regular spiking pyramidal cells in layers II/III | firing frequency (Hz) | 27.0 (24) | 27.0 (Hz) | Data Table |
Other | presubiculum intrinsically bursting cells in layers IV | firing frequency (Hz) | 68.0 (6) | 68.0 (Hz) | Data Table |