TABLE 1.
Summary of membrane properties of SCN-innervated SPZ neurons
| Parameter | Mean ± SE or % | Range | n | P |
|---|---|---|---|---|
| Resting membrane potential, mV | −55 ± 1 | −70 to −39 | 81 | 0.05 |
| Input resistance, MΩ | 1,133 ± 43 | 621 to 2,566 | 74 | <0.01 |
| Action potential amplitude, mV | 88 ± 3 | 61 to 116 | 25 | 0.96 |
| Amplitude of spike after hyperpolarization, mV | 20 ± 2 | 8 to 37 | 25 | 0.33 |
| Spontaneously active, %, Hz | 31% | 0.4 to 5.7 | 25/81 | <0.05 |
| Instantaneous inward rectification, % | 38% | 28/74 | <0.01 | |
| Time-dependent inward rectification, % | 18% | 13/74 | <0.01 | |
| Rebound low-threshold potentials, % | 43% | 32/74 | <0.01 |
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Values are expressed as means±SE, except for descriptive data that are noted as percentage of neurons that exhibited a particular active conductance (see methods). The table summarizes data from whole cell recordings from neurons in the region of SPZ, using patch pipettes filled with potassium gluconate–containing media. Of these neurons, biocytin labeling of 23 cells confirmed their localization within the boundaries of SPZ. P values apply to all measurements per category and are according to the Shapiro–Wilks test for normality of distributions.