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Article: Metabotropic glutamate receptor activation modulates epileptiform activity in the hippocampus.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Rutecki PA; Yang Y Neuroscience, 1997
Table 1Effects of 30μM ACPD on bicuculline-induced epileptiform activity (n=10 neurons)
*P<0.05 and **P<0.002 by Student's paired t-test.
| PDS duration (ms) | AHP amplitude (mV) | AHP half decay (ms) | Time between discharges (s) | Input resistance (MΩ) | Resting potential (mV) | |
| Control | 122.1±13.1 | −13.9±1.2 | 1 673±224 | 10.77±1.73 | 38.7±4.6 | −63.6±2.2 |
| ACPD | 118.6±13.5 | −11.6±3.6** | 1 156±194** | 4.25±0.45** | 42.7±4.3* | −63.3±2.3 |
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Hippocampus CA3 pyramidal cell | AHP amplitude (mV) | -13.9 ± 1.2 (10) | 13.9 (mV) | Data Table | |
| Hippocampus CA3 pyramidal cell | membrane time constant (s) | 10.77 ± 1.73 (10) | -- | Data Table | |
| Hippocampus CA3 pyramidal cell | input resistance (MΩ) | 38.7 ± 4.6 (10) | 38.7 (MΩ) | Data Table | |
| Hippocampus CA3 pyramidal cell | resting membrane potential (mV) | -63.6 ± 2.2 (10) | -63.6 (mV) | Data Table |