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Article: Sleep loss alters synaptic and intrinsic neuronal properties in mouse prefrontal cortex.

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Winters BD; Huang YH; Dong Y; Krueger JM
Brain Res., 2011


Table 1Intrinsic property averages±SEM for control and SD group cells.
ParameterControl (n=22)SD (n=27)
Break-in RMP (mV)−69.71±1.76−69.26±1.05
Ri at −100pA (MΩ)223.79±7.41238.40±8.89
Ri at +25pA (MΩ)329.77±16.33323.76±16.59
Latency 1st spike (ms)406.89±25.30433.36±19.39
Rheobase (pA)101.14±5.0699.07±5.08
AP threshold (mV)−33.50±0.93−35.14±0.61
AP amplitude (mV)70.70±1.2769.75±1.56
AP halfwidth (ms)0.98±0.030.98±0.03

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell first spike latency (ms) 406.89 ± 25.3 (22) 406.89 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell rheobase (pA) 101.14 ± 5.06 (22) 101.14 (pA) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell spike threshold (mV) -33.5 ± 0.93 (22) -33.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell spike amplitude (mV) 70.7 ± 1.27 (22) 70.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell spike half-width (ms) 0.98 ± 0.03 (22) 0.98 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell resting membrane potential (mV) -69.71 ± 1.76 (22) -69.71 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Medial Prefrontal Cortex Layer V/VI Pyramidal Cell input resistance (MΩ) 223.79 ± 7.41 (22) 223.79 (MΩ) Data Table