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Article: Role of protein kinase C in modulation of excitability of CA1 pyramidal neurons in the rat.

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Grabauskas G; Chapman H; Wheal HV
Neuroscience, 2006


Table 1Effect of indolactam V on intrinsic and spiking properties of CA1 pyramidal neurons
PropertyControlIndolactam V
Membrane potential (mV)−64.7±2.8−59.7±2.2
Spike amplitude (mV)89.7±5.491.2±5.5
Half-width (ms)1.4±0.181.57±0.12
Spike threshold (mV)−42.4±3.8−51±3.1⁎
Input resistance (MΩ)105±18140±12
Number of spikes/500 ms5.7±2.415±2⁎
Amplitude of mAHP (mV)5.2±1.66.8±2.18
Amplitude of sAHP (mV)4.1±1.20.22±0.22⁎
Values are expressed as mean±SD.⁎Significantly different at P<0.05, n=15.

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell spike half-width (ms) 1.4 ± 0.18 (15) 1.4 (ms) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -42.4 ± 3.8 (15) -42.4 (mV) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 105.0 ± 18.0 (15) 105.0 (MΩ) Data Table
Hippocampus CA1 pyramidal cell medium AHP amplitude (mV) 5.2 ± 1.6 (15) 5.2 (mV) Data Table
Hippocampus CA1 pyramidal cell slow AHP amplitude (mV) 4.1 ± 1.2 (15) 4.1 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -64.7 ± 2.8 (15) -64.7 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 89.7 ± 5.4 (15) 89.7 (mV) Data Table