Table 2Values of EPSP, IE and AP (mean±SD) before and after HFS in type-A and type-B neurons evaluated in separate groups of neurons (condition 1 and 2) or in the same neuron alternating EPSP and IE recordings (condition 3)
Type-A neurons
Condition 1 (n=4)
Condition 2 (n=5)
Condition 3 (n=1)
Control
HFS
Control
HFS
Control
HFS
EPSP
Amplitude (mV)
2.86±1.56
3.68±0.4
2.42±0.9
3.2±0.6
2.6
3.1
Slope (mV/ms)
0.45±0.25
0.57±0.07
0.52
0.76
Decay time constant τ (ms)
45.1±15.5
58.3±3.9
48.7
68.9
Condition 1 (n=8)
Condition 2 (n=6)
Condition 3 (n=3)
Control
HFS
Control
HFS
Control
HFS
IE
SF (spikes/s)
2.6±1.1
4.2±1.3
3±0.7
4.5±0.6
EF (spikes)
12.3±5.8
21.3±6.8
10.5±3.6
17.8±4.5
11.2±2.5
17.6±3.8
Rin (MΩ)
640.6±240.4
770.6±65.5
720.2±160.1
866.1±28.9
AP
AHP amplitude (mV)
−22.3±3
−19.5±2
ISS (mv/s)
57.89±10.2
81.93±6.8
Type-B neurons
Condition 1 (n=10)
Condition 2 (n=10)
Condition 3 (n=3)
Control
HFS
Control
HFS
Control
HFS
EPSP
Amplitude (mV)
4.32±1.4
7±0.9⁎
5.2±1.5
8.2±0.5⁎
4.7±1.3
6.9±0.5⁎
Slope (mV/ms)
1.26±0.99
1.99±0.25⁎
2.2±0.7
3.1±0.2⁎
Decay time constant τ (ms)
18.8±8.1
27±4.5⁎
19.5±5.1
27.7±1.8⁎
Condition 1 (n=6)
Condition 2 (n=6)
Condition 3 (n=2)
Control
HFS
Control
HFS
Control
HFS
IE
SF (spikes/s)
5.5±3.9
14.1±4.5⁎
6.4±2.6
12±0.7⁎
EF (spikes)
13.8±3.6
25.1±7.4
12.4±2.5
22.3±5.4⁎
15.4±2.9
24.9±1.7
Rin (MΩ)
272±113.6
348.4±51.2
197±99.6
249.3±23.8
AP
AHP amplitude (mV)
−16.2±1.3
−13.3±1.2
ISS (mv/s)
122.2±18.2
237.14±35.7⁎
⁎Indicates significant difference (ANOVA and Tukey's post hoc test, P<0.05) in the change induced by HFS between type-A and type-B neurons.