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Article: Increased spike broadening and slow afterhyperpolarization in CA1 pyramidal cells of streptozotocin-induced diabetic rats.

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Kamal A; Artola A; Biessels GJ; Gispen WH; Ramakers GM
Neuroscience, 2003


Table 1Passive and active properties of CA1 pyramidal cells from STZ-diabetic and control rats
STZ-diabeticControl
RMP (mV)−72.65 1.14 (56)−71.93 1.02 (53)
Rin (MΩ)33.36 2.05 (30)32.73 1.64 (25)
τmembrane (ms)8.24 0.52 (30)8.00 0.47 (25)
AP amplitude (mV)97.43 4.6291.64 2.77
AP duration (ms)1.87 0.241.80 0.21
No significant differences in the RMP, Rin, τmembrane, AP amplitude and AP duration were detected between CA1 pyramidal cells from STZ-diabetic and control rats.

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell membrane time constant (ms) 8.0 (25) 8.0 (ms) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 91.642 91.64 (mV) Data Table
Hippocampus CA1 pyramidal cell spike width (ms) 1.8 1.8 (ms) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -71.931 (53) -71.93 (mV) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 32.731 (25) 32.73 (MΩ) Data Table