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Article: Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Gant JC; Sama MM; Landfield PW; Thibault O J. Neurosci., 2006
Table 1.
Basic neuronal and experimental properties: neuronal parameters for all recorded CA1 neurons
| Age | |||||
|---|---|---|---|---|---|
| 4 months (n = 19) | 10 months (n = 16) | 12 months (n = 21) | 14 months (n = 15) | 23 months (n = 21) | |
| Input resistance (MΩ) | 55.76 ± 2.84 | 56.25 ± 3.66 | 52.55 ± 2.647 | 56.02 ± 3.42 | 50.87 ± 2.87 |
| Resting membrane potential (mV) | −62.0 ± 0.41 | −62.44 ± 0.61 | −62.71 ± 0.47 | −61.47 ± 0.60 | −62.67 ± 0.50 |
| Action potential amplitude (mV) | 77.37 ± 1.32 | 77.13 ± 1.22 | 76.91 ± 1.19 | 79.20 ± 1.50 | 78.0 ± 1.15 |
| Electrode resistance (MΩ) | 100.11 ± 7.09 | 106.13 ± 6.34 | 99.90 ± 5.81 | 100.93 ± 8.91 | 97.8 ± 3.97 |
| RSS hyperpolarization (mV) | −2.77 ± 0.40 | −3.21 ± 0.48 | −2.75 ± 0.28 | −2.23 ± 0.34 | −2.55 ± 0.26 |
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Basic membrane and experimental variables for CA1 pyramidal neurons across all age groups. No significant aging effect was detected on any of these baseline variables. RSS hyperpolarization was measured at its peak level during RSS from a holding potential of −70 mV. All values are means ± SEM.