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Article: Physiological and morphological characterization of dentate granule cells in the p35 knock-out mouse hippocampus: evidence for an epileptic circuit.

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Patel LS; Wenzel HJ; Schwartzkroin PA
J. Neurosci., 2004


Table 1.

Passive properties of p35 wild-type and knock-out GCs

p35 wild type p35 knock-out
Number 33 38
Resting membrane potential (mV) −75.5 ± 1.27 −77.2 ± 1.04
Input resistance (MΩ) 81.9 ± 5.77 82.9 ± 4.39
Time constant (msec) 7.48 ± 0.49 8.38 ± 0.67
Action potential Amplitude (mV) 77.5 ± 1.49 76.0 ± 1.14
Threshold (mV) −46.7 ± 1.8 −44.3 ± 1.86
Duration (msec) 2.11 ± 0.06 2.37 ± 0.05

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Dentate gyrus granule cell membrane time constant (msec) 7.48 ± 0.49 (33) 7.48 (ms) Data Table
Dentate gyrus granule cell spike amplitude (mV) 77.5 ± 1.49 (33) 77.5 (mV) Data Table
Dentate gyrus granule cell spike threshold (mV) -46.7 ± 1.8 (33) -46.7 (mV) Data Table
Dentate gyrus granule cell spike width (msec) 2.11 ± 0.06 (33) 2.11 (ms) Data Table
Dentate gyrus granule cell resting membrane potential (mV) -75.5 ± 1.27 (33) -75.5 (mV) Data Table
Dentate gyrus granule cell input resistance (MΩ) 81.9 ± 5.77 (33) 81.9 (MΩ) Data Table