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Article: Major differences in inhibitory synaptic transmission onto two neocortical interneuron subclasses.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Bacci A; Rudolph U; Huguenard JR; Prince DA J. Neurosci., 2003
Table 3.
Effects of 10 μm loreclezole and 200 nm zolpidem on sIPSCs in FS and LTS interneurons
| FS | LTS | |||||||
|---|---|---|---|---|---|---|---|---|
| Control | LCZ | Control | ZOLP | Control | LCZ | Control | ZOLP | |
| Amplitude (pA) | 31.8 ± 3.3 | 33.8 ± 2.6 | 28.8 ± 2.8 | 38.6 ± 4.5* | 14.3 ± 1.6 | 14.5 ± 1.9 | 17.2 ± 2.0 | 18.6 ± 2.4 |
| Frequency (Hz) | 8.7 ± 1.5 | 14.4 ± 2.3* | 3.4 ± 1.0 | 3.8 ± 1.1 | 1.1 ± 0.32 | 1.2 ± 0.4 | 0.47 ± 0.1 | 0.4 ± 0.07 |
| Half-width (msec) | 5.2 ± 0.4 | 17.8 ± 1.1*** | 4.5 ± 0.6 | 7.2 ± 0.9* | 10.8 ± 3.0 | 13.7 ± 3.9* | 7.5 ± 1.0 | 10.3 ± 1.9 |
| τd,w (msec) | 6.11 ± 0.7 | 23.5 ± 2.3*** | 11.7 ± 2.3 | 16.9 ± 3.2** | 38.4 ± 17 | 87.1 ± 17* | 71.7 ± 18 | 87.9 ± 29 |
| Charge (nC) | 0.2 ± 0.01 | 0.7 ± 0.11** | 0.2 ± 0.02 | 0.5 ± 0.07** | 0.53 ± 0.2 | 0.82 ± 0.2* | 1.0 ± 0.2 | 1.2 ± 0.3 |
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LCZ, Loreclezole; ZOLP, zolpidem. All values are means ± SEM. Loreclezole: n = 6 for FS interneurons; n = 6 for LTS interneurons. Zolpidem: n = 7 for FS interneurons; n = 6 for LTS interneurons. *p<0.05; **p<0.01; ***p < 0.001; paired t test.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|