Table 3.
Frequency of induced AP during steps and membrane oscillations during ramps with and without CAR
| Mean AP Frequency During Steps | Mean Oscillation Frequency During Ramps | ||||
|---|---|---|---|---|---|
| Age Group | 1st ISI | Steady state (middle + last + ISI) | Overall | TTX + blockers | TTX + blockers + CAR |
| P9–12 | 46.4 ± 3.7 | 23.4 ± 0.8 | 31.1 ± 2.2 | 24.6 ± 3.8 | 41.7 ± 4.3 |
| P13–16 | 45.4 ± 3.9 | 22.4 ± 1.2 | 30.1 ± 2.3 | 35.1 ± 2.9 | 55.2 ± 3.1 |
| P17–25 | 55.4 ± 4.7 | 24.1 ± 1.4 | 36.5 ± 4.1 | 51.6 ± 4.1 | 59.2 ± 4.7 |
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Values are means ± SE of frequency (in Hz) of induced action potentials (AP) during steps and of membrane oscillations during ramps and after exposure to carbachol (CAR). AP data were calculated from the 180-pA calcium current depolarization step (i.e., last step). Oscillation data were composed from analysis of peaks in the power spectra in the presence of fast synaptic blockers and tetrodotoxin (TTX). ISI, interspike interval.