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Article: Frequency dependence of CA3 spike phase response arising from h-current properties.

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Borel M; Guadagna S; Jang HJ; Kwag J; Paulsen O
Front Cell Neurosci, 2013


Passive membrane properties and resonance properties of CA3 and CA1 pyramidal neurons.

CA3 CA1
RMP (mV) -54 ± 1 (40) -57 ± 1 (21) n.s.
Rin (MΩ) 248 ± 10 (40) 212 ± 16 (21) n.s.
Sag 0.16 ± 0.01 (40) 0.30 ± 0.02 (21) ***
FRes (Hz) 1.19 ± 0.09 (15) 2.49 ± 0.17 (19) ***
Q-value 1.06 ± 0.01 (15) 1.15 ± 0.01 (19) ***

Data are presented as mean ± SEM; numbers in parenthesis represent number of cells. Cells were recorded at 30 °C. RMP, resting membrane potential; Sag measured at -60 mV; Frequency preference (FRes) and resonance strength (Q-value) measured at -70 mV.

p < 0.001, n.s.: p > 0.05, unpaired two-sample Student's t-test.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA3 pyramidal cell sag amplitude 0.16 ± 0.01 (40) 0.16 (mV) Data Table
Hippocampus CA1 pyramidal cell sag amplitude 0.3 ± 0.02 (21) 0.3 (mV) Data Table
Hippocampus CA3 pyramidal cell other (Hz) 1.19 ± 0.09 (15) -- Data Table
Hippocampus CA1 pyramidal cell other (Hz) 2.49 ± 0.17 (19) -- Data Table
Hippocampus CA3 pyramidal cell other 1.06 ± 0.01 (15) 1.06 (None) Data Table
Hippocampus CA1 pyramidal cell other 1.15 ± 0.01 (19) 1.15 (None) Data Table
Hippocampus CA3 pyramidal cell resting membrane potential (mV) -54.0 ± 1.0 (40) -54.0 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -57.0 ± 1.0 (21) -57.0 (mV) Data Table
Hippocampus CA3 pyramidal cell input resistance (MΩ) 248.0 ± 10.0 (40) 248.0 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 212.0 ± 16.0 (21) 212.0 (MΩ) Data Table