AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Highly differentiated cellular and circuit properties of infralimbic pyramidal neurons projecting to the periaqueductal gray and amygdala.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Ferreira AN; Yousuf H; Dalton S; Sheets PL
Front Cell Neurosci, 2015


Intrinsic electrophysiological properties of IL neurons projecting to the PAG or BLA.

CP (n = 26) L3/5 CA (n = 20) L2 CA (n = 10) Significance
Subthreshold
Resting membrane potential (mV) -68.5 ± 1.4 -66.1 ± 3.3 -76.0 ± 2.1 b, c
Input resistance (MΩ) 106 ± 4.4 196 ± 13 94.3 ± 8.7 a, c
Voltage sag (%) 8.8 ± 1.1 6.3 ± 1.4 -0.9 ± 0.4 b, c
Voltage overshoot (%) 13.0 ± 1.3 7.9 ± 1.1 0.7 ± 1.7 a, b, c
Resonant frequency (Hz) 2.2 ± 0.2 1.3 ± 0.3 0.7 ± 0.1 a, b
Suprathreshold
AP threshold (mV) -38.4 ± 1.2 -32.5 ± 2.1 -38.4 ± 2.3 None
AP amplitude (mV) 74.6 ± 1.9 63.9 ± 2.8 68.0 ± 3.4 a
AP halfwidth (ms) 0.6 ± 0.03 0.67 ± 0.03 0.62 ± 0.03 None
Frequency current slope (Hz/pA) 0.15 ± 0.02 0.15 ± 0.01 0.17 ± 0.01 b
Fast SFA (3rd/5th) 0.93 ± 0.02 0.90 ± 0.01 0.89 ± 0.01 a
Slow SFA (2nd/Last) 0.76 ± 0.04 0.61 ± 0.03 0.69 ± 0.02 a
Fast after-hyperpolarization (mV) -9.5 ± 0.8 -10.0 ± 1.6 -10.9 ± 1.3 None
CP, cortico-PAG neurons (18 animals); L3/5 CA, layer 3/5 CA neurons (14 animals); L2 CA, layer 2 CA neurons (seven animals). Data shown as mean ± SE of the mean. a, CP vs. L3/5 CA; b, CP vs. L2 CA; c, L3/5 CA vs. L2 CA. ANOVA (normally distributed data) or Kruskal–Wallace test (non-normally distributed data) followed by a Bonferroni post hoc analysis for multiple comparisons was used to determine statistical significance which was set at p < 0.05.
Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex uncharacterized cell Infralimbic cortex layer 3/5 pyramidal neuron projecting to basolateral amygdala input resistance (MΩ) 196.0 ± 13.0 (20) 196.0 (MΩ) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 2 pyramidal neuron projecting to basolateral amygdala input resistance (MΩ) 94.3 ± 8.7 (10) 94.3 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Infralimbic cortex layer 5 pyramidal neuron projecting to periaqueductal gray sag ratio 8.8 ± 1.1 (26) 0.088 (ratio) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 3/5 pyramidal neuron projecting to basolateral amygdala sag ratio 6.3 ± 1.4 (20) 0.063 (ratio) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 2 pyramidal neuron projecting to basolateral amygdala sag ratio -0.9 ± 0.4 (10) -0.009 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Infralimbic cortex layer 5 pyramidal neuron projecting to periaqueductal gray spike threshold (mV) -38.4 ± 1.2 (26) -38.4 (mV) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 3/5 pyramidal neuron projecting to basolateral amygdala spike threshold (mV) -32.5 ± 2.1 (20) -32.5 (mV) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 2 pyramidal neuron projecting to basolateral amygdala spike threshold (mV) -38.4 ± 2.3 (10) -38.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Infralimbic cortex layer 5 pyramidal neuron projecting to periaqueductal gray spike amplitude (mV) 74.6 ± 1.9 (26) 74.6 (mV) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 3/5 pyramidal neuron projecting to basolateral amygdala spike amplitude (mV) 63.9 ± 2.8 (20) 63.9 (mV) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 2 pyramidal neuron projecting to basolateral amygdala spike amplitude (mV) 68.0 ± 3.4 (10) 68.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Infralimbic cortex layer 5 pyramidal neuron projecting to periaqueductal gray resting membrane potential (mV) -68.5 ± 1.4 (26) -68.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Infralimbic cortex layer 5 pyramidal neuron projecting to periaqueductal gray spike half-width (ms) 0.6 ± 0.03 (26) 0.6 (ms) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 3/5 pyramidal neuron projecting to basolateral amygdala spike half-width (ms) 0.67 ± 0.03 (20) 0.67 (ms) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 2 pyramidal neuron projecting to basolateral amygdala spike half-width (ms) 0.62 ± 0.03 (10) 0.62 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Infralimbic cortex layer 5 pyramidal neuron projecting to periaqueductal gray FI slope (Hz/pA) 0.15 ± 0.02 (26) 150.0 (Hz/nA) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 3/5 pyramidal neuron projecting to basolateral amygdala FI slope (Hz/pA) 0.15 ± 0.01 (20) 150.0 (Hz/nA) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 2 pyramidal neuron projecting to basolateral amygdala FI slope (Hz/pA) 0.17 ± 0.01 (10) 170.0 (Hz/nA) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 3/5 pyramidal neuron projecting to basolateral amygdala resting membrane potential (mV) -66.1 ± 3.3 (20) -66.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Infralimbic cortex layer 5 pyramidal neuron projecting to periaqueductal gray adaptation ratio 0.76 ± 0.04 (26) 0.76 (ratio) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 3/5 pyramidal neuron projecting to basolateral amygdala adaptation ratio 0.61 ± 0.03 (20) 0.61 (ratio) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 2 pyramidal neuron projecting to basolateral amygdala adaptation ratio 0.69 ± 0.02 (10) 0.69 (ratio) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 2 pyramidal neuron projecting to basolateral amygdala resting membrane potential (mV) -76.0 ± 2.1 (10) -76.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Infralimbic cortex layer 5 pyramidal neuron projecting to periaqueductal gray fast AHP amplitude (mV) -9.5 ± 0.8 (26) 9.5 (mV) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 3/5 pyramidal neuron projecting to basolateral amygdala fast AHP amplitude (mV) -10.0 ± 1.6 (20) 10.0 (mV) Data Table
Neocortex uncharacterized cell Infralimbic cortex layer 2 pyramidal neuron projecting to basolateral amygdala fast AHP amplitude (mV) -10.9 ± 1.3 (10) 10.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Infralimbic cortex layer 5 pyramidal neuron projecting to periaqueductal gray input resistance (MΩ) 106.0 ± 4.4 (26) 106.0 (MΩ) Data Table