Article: Heterogeneity in the basic membrane properties of postnatal gonadotropin-releasing hormone neurons in the mouse.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Sim JA; Skynner MJ; Herbison AE J. Neurosci., 2001
Juvenile mice (n= 31) | Adult female mice | |||
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All adult mice (n= 44) | Estrous mice (n = 17) | Diestrous mice (n = 27) | ||
Resting membrane potential (mV) | −65.4 ± 1.5 | −69.2 ± 1.1 | −68.6 ± 2.1 | −69.1 ± 1.2 |
(−47 to −85) | (−52 to −85) | |||
Input resistance (GΩ) | 1.1 ± 0.2 | 1.5 ± 0.1 | 1.6 ± 0.2 | 1.4 ± 0.1 |
(0.03–2.8) | (0.36–3.18) | |||
Membrane time constant (msec) | 39.0 ± 4.4 | 44.8 ± 3.5 | 45.5 ± 4.1 | 43.5 ± 5.0 |
(3.0–91.1) | (12.1–110.3) | |||
Threshold potential of spike (mV) | −39.7 ± 1.7 | −33.9 ± 2.9 | −36.0 ± 0.7 | −38.5 ± 1.6 |
(−25.5 to −50.3) | (−27.7 to −51.8) | |||
Amplitude of spike (mV) | 83.1 ± 2.8 | 84.2 ± 1.8 | 85.2 ± 3.2 | 83.6 ± 2.1 |
(54.0–101.3) | (67.4–121.3) | |||
Overshoot of spike (mV) | 18.5 ± 2.0 | 15.4 ± 2.2 | 18.3 ± 4.2 | 13.5 ± 2.4 |
(−2.1 to 33.9) | (−4.5 to 49.5) | |||
Duration of spike (msec) | 1.8 ± 0.1 | 2.0 ± 0.1 | 1.6 ± 0.1 | 2.3 ± 0.1* |
(1.2–2.8) | (0.8–3.4) |
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The numbers of GnRH neurons analyzed are given in parentheses. Adult GnRH neurons are further divided to show their properties in estrous and diestrous mice. A significant (* p < 0.05) difference in the duration of their action potential values was detected. Values are mean ± SEM, whereas ranges of values obtained are shown in parentheses.