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Article: A critical period for nicotine-induced disruption of synaptic development in rat auditory cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Aramakis VB; Hsieh CY; Leslie FM; Metherate R J. Neurosci., 2000
Table 3.
Density of α7 mRNA and [125I]α-BTX binding sites in auditory cortex of rats treated from P8-12 with saline or nicotine (CNE)
| α7 mRNA (cpm/mg tissue) | [125I]α-BTX (fmol/mg tissue) | |||
|---|---|---|---|---|
| Saline | CNE | Saline | CNE | |
| P13 | ||||
| Layer II/III | 1292 ± 94 | 1681 ± 116 | 3.2 ± 0.1 | 3.3 ± 0.3 |
| Layer IV | 1529 ± 213 | 1950 ± 149 | 4.1 ± 0.1 | 4.4 ± 0.2 |
| Layer V/VI | 1611 ± 188 | 1915 ± 230 | 5.0 ± 0.1 | 5.3 ± 0.2 |
| P23 | ||||
| Layer II/III | 1134 ± 120 | 1212 ± 28 | 2.1 ± 0.1 | 2.4 ± 0.33-a |
| Layer IV | 1267 ± 130 | 1336 ± 59 | 2.5 ± 0.1 | 2.9 ± 0.23-a |
| Layer V/VI | 1291 ± 117 | 1361 ± 53 | 3.8 ± 0.1 | 4.3 ± 0.23-a |
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Data are mean ± SEM for four animals in each group. Saline- versus nicotine-treated groups compared with repeated measures ANOVA.
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↵F3-a p < 0.001.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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